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Page 1
Increased insulin sensitivity despite lipodystrophy in Crebbp heterozygous mice.
Yamauchi T, Oike Y, Kamon J, Waki H, Komeda K, Tsuchida A, Date Y, Li MX, Miki H, Akanuma Y, Nagai R, Kimura S, Saheki T, Nakazato M, Naitoh T, Yamamura K, Kadowaki T. Yamauchi T, et al. Among authors: oike y. Nat Genet. 2002 Feb;30(2):221-6. doi: 10.1038/ng829. Epub 2002 Jan 30. Nat Genet. 2002. PMID: 11818964
Impaired insulin signaling in endothelial cells reduces insulin-induced glucose uptake by skeletal muscle.
Kubota T, Kubota N, Kumagai H, Yamaguchi S, Kozono H, Takahashi T, Inoue M, Itoh S, Takamoto I, Sasako T, Kumagai K, Kawai T, Hashimoto S, Kobayashi T, Sato M, Tokuyama K, Nishimura S, Tsunoda M, Ide T, Murakami K, Yamazaki T, Ezaki O, Kawamura K, Masuda H, Moroi M, Sugi K, Oike Y, Shimokawa H, Yanagihara N, Tsutsui M, Terauchi Y, Tobe K, Nagai R, Kamata K, Inoue K, Kodama T, Ueki K, Kadowaki T. Kubota T, et al. Among authors: oike y. Cell Metab. 2011 Mar 2;13(3):294-307. doi: 10.1016/j.cmet.2011.01.018. Cell Metab. 2011. PMID: 21356519 Free article.
The secreted protein ANGPTL2 promotes metastasis of osteosarcoma cells through integrin α5β1, p38 MAPK, and matrix metalloproteinases.
Odagiri H, Kadomatsu T, Endo M, Masuda T, Morioka MS, Fukuhara S, Miyamoto T, Kobayashi E, Miyata K, Aoi J, Horiguchi H, Nishimura N, Terada K, Yakushiji T, Manabe I, Mochizuki N, Mizuta H, Oike Y. Odagiri H, et al. Among authors: oike y. Sci Signal. 2014 Jan 21;7(309):ra7. doi: 10.1126/scisignal.2004612. Sci Signal. 2014. PMID: 24448647
Angiopoietin-like protein 2 renders colorectal cancer cells resistant to chemotherapy by activating spleen tyrosine kinase-phosphoinositide 3-kinase-dependent anti-apoptotic signaling.
Horiguchi H, Endo M, Miyamoto Y, Sakamoto Y, Odagiri H, Masuda T, Kadomatsu T, Tanoue H, Motokawa I, Terada K, Morioka MS, Manabe I, Baba H, Oike Y. Horiguchi H, et al. Among authors: oike y. Cancer Sci. 2014 Dec;105(12):1550-9. doi: 10.1111/cas.12554. Epub 2014 Nov 5. Cancer Sci. 2014. PMID: 25287946 Free PMC article.
ANGPTL2 increases bone metastasis of breast cancer cells through enhancing CXCR4 signaling.
Masuda T, Endo M, Yamamoto Y, Odagiri H, Kadomatsu T, Nakamura T, Tanoue H, Ito H, Yugami M, Miyata K, Morinaga J, Horiguchi H, Motokawa I, Terada K, Morioka MS, Manabe I, Iwase H, Mizuta H, Oike Y. Masuda T, et al. Among authors: oike y. Sci Rep. 2015 Mar 16;5:9170. doi: 10.1038/srep09170. Sci Rep. 2015. PMID: 25773070 Free PMC article.
Interstitial pneumonia induced by bleomycin treatment is exacerbated in Angptl2-deficient mice.
Motokawa I, Endo M, Terada K, Horiguchi H, Miyata K, Kadomatsu T, Morinaga J, Sugizaki T, Ito T, Araki K, Morioka MS, Manabe I, Samukawa T, Watanabe M, Inoue H, Oike Y. Motokawa I, et al. Among authors: oike y. Am J Physiol Lung Cell Mol Physiol. 2016 Oct 1;311(4):L704-L713. doi: 10.1152/ajplung.00005.2016. Epub 2016 Aug 19. Am J Physiol Lung Cell Mol Physiol. 2016. PMID: 27542805 Free article.
295 results