Okkenhaug K - Search Results

1

Protein kinase B controls transcriptional programs that direct cytotoxic T cell fate but is dispensable for T cell metabolism.

Macintyre AN, Finlay D, Preston G, Sinclair LV, Waugh CM, Tamas P, Feijoo C, Okkenhaug K, Cantrell DA. Macintyre AN, et al. Among authors: okkenhaug k. Immunity. 2011 Feb 25;34(2):224-36. doi: 10.1016/j.immuni.2011.01.012. Epub 2011 Feb 3. Immunity. 2011. PMID: 21295499 Free PMC article.

2

Tetherin antagonism by SARS-CoV-2 ORF3a and spike protein enhances virus release.

Stewart H, Palmulli R, Johansen KH, McGovern N, Shehata OM, Carnell GW, Jackson HK, Lee JS, Brown JC, Burgoyne T, Heeney JL, Okkenhaug K, Firth AE, Peden AA, Edgar JR. Stewart H, et al. Among authors: okkenhaug k. EMBO Rep. 2023 Dec 6;24(12):e57224. doi: 10.15252/embr.202357224. Epub 2023 Oct 11. EMBO Rep. 2023. PMID: 37818801 Free PMC article.

3

Tissue-resident B cells orchestrate macrophage polarisation and function.

Suchanek O, Ferdinand JR, Tuong ZK, Wijeyesinghe S, Chandra A, Clauder AK, Almeida LN, Clare S, Harcourt K, Ward CJ, Bashford-Rogers R, Lawley T, Manz RA, Okkenhaug K, Masopust D, Clatworthy MR. Suchanek O, et al. Among authors: okkenhaug k. Nat Commun. 2023 Nov 4;14(1):7081. doi: 10.1038/s41467-023-42625-4. Nat Commun. 2023. PMID: 37925420 Free PMC article.

4

Phosphatidylinositol-3-OH kinase and nutrient-sensing mTOR pathways control T lymphocyte trafficking.

Sinclair LV, Finlay D, Feijoo C, Cornish GH, Gray A, Ager A, Okkenhaug K, Hagenbeek TJ, Spits H, Cantrell DA. Sinclair LV, et al. Among authors: okkenhaug k. Nat Immunol. 2008 May;9(5):513-21. doi: 10.1038/ni.1603. Epub 2008 Apr 6. Nat Immunol. 2008. PMID: 18391955 Free PMC article.

5

PDK1 regulation of mTOR and hypoxia-inducible factor 1 integrate metabolism and migration of CD8+ T cells.

Finlay DK, Rosenzweig E, Sinclair LV, Feijoo-Carnero C, Hukelmann JL, Rolf J, Panteleyev AA, Okkenhaug K, Cantrell DA. Finlay DK, et al. Among authors: okkenhaug k. J Exp Med. 2012 Dec 17;209(13):2441-53. doi: 10.1084/jem.20112607. Epub 2012 Nov 26. J Exp Med. 2012. PMID: 23183047 Free PMC article.

6

Phosphoinositide 3-kinase in T cell activation and survival.

Okkenhaug K, Bilancio A, Emery JL, Vanhaesebroeck B. Okkenhaug K, et al. Biochem Soc Trans. 2004 Apr;32(Pt 2):332-5. doi: 10.1042/bst0320332. Biochem Soc Trans. 2004. PMID: 15046602 Review.

7

T cell receptor-induced phosphoinositide-3-kinase p110delta activity is required for T cell localization to antigenic tissue in mice.

Jarmin SJ, David R, Ma L, Chai JG, Dewchand H, Takesono A, Ridley AJ, Okkenhaug K, Marelli-Berg FM. Jarmin SJ, et al. Among authors: okkenhaug k. J Clin Invest. 2008 Mar;118(3):1154-64. doi: 10.1172/JCI33267. J Clin Invest. 2008. PMID: 18259608 Free PMC article.

8

MAPK, phosphatidylinositol 3-kinase, and mammalian target of rapamycin pathways converge at the level of ribosomal protein S6 phosphorylation to control metabolic signaling in CD8 T cells.

Salmond RJ, Emery J, Okkenhaug K, Zamoyska R. Salmond RJ, et al. Among authors: okkenhaug k. J Immunol. 2009 Dec 1;183(11):7388-97. doi: 10.4049/jimmunol.0902294. Epub 2009 Nov 16. J Immunol. 2009. PMID: 19917692

9

Genetic or pharmaceutical blockade of phosphoinositide 3-kinase p110δ prevents chronic rejection of heart allografts.

Ying H, Fu H, Rose ML, McCormack AM, Sarathchandra P, Okkenhaug K, Marelli-Berg FM. Ying H, et al. Among authors: okkenhaug k. PLoS One. 2012;7(3):e32892. doi: 10.1371/journal.pone.0032892. Epub 2012 Mar 30. PLoS One. 2012. PMID: 22479345 Free PMC article.

10

Phosphoinositide 3-kinase δ gene mutation predisposes to respiratory infection and airway damage.

Angulo I, Vadas O, Garçon F, Banham-Hall E, Plagnol V, Leahy TR, Baxendale H, Coulter T, Curtis J, Wu C, Blake-Palmer K, Perisic O, Smyth D, Maes M, Fiddler C, Juss J, Cilliers D, Markelj G, Chandra A, Farmer G, Kielkowska A, Clark J, Kracker S, Debré M, Picard C, Pellier I, Jabado N, Morris JA, Barcenas-Morales G, Fischer A, Stephens L, Hawkins P, Barrett JC, Abinun M, Clatworthy M, Durandy A, Doffinger R, Chilvers ER, Cant AJ, Kumararatne D, Okkenhaug K, Williams RL, Condliffe A, Nejentsev S. Angulo I, et al. Among authors: okkenhaug k. Science. 2013 Nov 15;342(6160):866-71. doi: 10.1126/science.1243292. Epub 2013 Oct 17. Science. 2013. PMID: 24136356 Free PMC article.

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