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Antidepressants inhibit Nav1.3, Nav1.7, and Nav1.8 neuronal voltage-gated sodium channels more potently than Nav1.2 and Nav1.6 channels expressed in Xenopus oocytes.
Horishita T, Yanagihara N, Ueno S, Okura D, Horishita R, Minami T, Ogata Y, Sudo Y, Uezono Y, Sata T, Kawasaki T. Horishita T, et al. Among authors: okura d. Naunyn Schmiedebergs Arch Pharmacol. 2017 Dec;390(12):1255-1270. doi: 10.1007/s00210-017-1424-x. Epub 2017 Sep 14. Naunyn Schmiedebergs Arch Pharmacol. 2017. PMID: 28905186
Neurosteroids allopregnanolone sulfate and pregnanolone sulfate have diverse effect on the α subunit of the neuronal voltage-gated sodium channels Nav1.2, Nav1.6, Nav1.7, and Nav1.8 expressed in xenopus oocytes.
Horishita T, Yanagihara N, Ueno S, Sudo Y, Uezono Y, Okura D, Minami T, Kawasaki T, Sata T. Horishita T, et al. Among authors: okura d. Anesthesiology. 2014 Sep;121(3):620-31. doi: 10.1097/ALN.0000000000000296. Anesthesiology. 2014. PMID: 24809977 Free article.
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