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Immunoregulatory mechanisms triggered by viral infections protect from type 1 diabetes in mice.
J Clin Invest. 2009 Jun;119(6):1515-23. doi: 10.1172/JCI38503. Epub 2009 May 26.
J Clin Invest. 2009.
PMID: 19478458
Free PMC article.
Transforming growth factor-beta suppresses the activation of CD8+ T-cells when naive but promotes their survival and function once antigen experienced: a two-faced impact on autoimmunity.
Filippi CM, Juedes AE, Oldham JE, Ling E, Togher L, Peng Y, Flavell RA, von Herrath MG.
Filippi CM, et al. Among authors: oldham je.
Diabetes. 2008 Oct;57(10):2684-92. doi: 10.2337/db08-0609. Epub 2008 Aug 8.
Diabetes. 2008.
PMID: 18689691
Free PMC article.
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Essential role for TLR9 in prime but not prime-boost plasmid DNA vaccination to activate dendritic cells and protect from lethal viral infection.
Rottembourg D, Filippi CM, Bresson D, Ehrhardt K, Estes EA, Oldham JE, von Herrath MG.
Rottembourg D, et al. Among authors: oldham je.
J Immunol. 2010 Jun 15;184(12):7100-7. doi: 10.4049/jimmunol.0803935. Epub 2010 May 7.
J Immunol. 2010.
PMID: 20483769
Free PMC article.
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TLR2 signaling improves immunoregulation to prevent type 1 diabetes.
Filippi CM, Ehrhardt K, Estes EA, Larsson P, Oldham JE, von Herrath MG.
Filippi CM, et al. Among authors: oldham je.
Eur J Immunol. 2011 May;41(5):1399-409. doi: 10.1002/eji.200939841.
Eur J Immunol. 2011.
PMID: 21469083
Free PMC article.
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Expression level of a pancreatic neo-antigen in beta cells determines degree of diabetes pathogenesis.
Martinic MM, Huber C, Coppieters K, Oldham JE, Gavin AL, von Herrath MG.
Martinic MM, et al. Among authors: oldham je.
J Autoimmun. 2010 Dec;35(4):404-13. doi: 10.1016/j.jaut.2010.08.006. Epub 2010 Oct 6.
J Autoimmun. 2010.
PMID: 20932718
Free PMC article.
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Prolonged exposure of naïve CD8+ T cells to interleukin-7 or interleukin-15 stimulates proliferation without differentiation or loss of telomere length.
Wallace DL, Bérard M, Soares MV, Oldham J, Cook JE, Akbar AN, Tough DF, Beverley PC.
Wallace DL, et al. Among authors: oldham j.
Immunology. 2006 Oct;119(2):243-53. doi: 10.1111/j.1365-2567.2006.02429.x.
Immunology. 2006.
PMID: 17005004
Free PMC article.
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