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N-Arylalkyl pseudopeptide inhibitors of farnesyltransferase.
deSolms SJ, Giuliani EA, Graham SL, Koblan KS, Kohl NE, Mosser SD, Oliff AI, Pompliano DL, Rands E, Scholz TH, Wiscount CM, Gibbs JB, Smith RL. deSolms SJ, et al. Among authors: oliff ai. J Med Chem. 1998 Jul 2;41(14):2651-6. doi: 10.1021/jm9800907. J Med Chem. 1998. PMID: 9651171
Farnesyltransferase inhibitors versus Ras inhibitors.
Gibbs JB, Graham SL, Hartman GD, Koblan KS, Kohl NE, Omer CA, Oliff A. Gibbs JB, et al. Among authors: oliff a. Curr Opin Chem Biol. 1997 Aug;1(2):197-203. doi: 10.1016/s1367-5931(97)80010-5. Curr Opin Chem Biol. 1997. PMID: 9667853 Review.
Mouse mammary tumor virus-Ki-rasB transgenic mice develop mammary carcinomas that can be growth-inhibited by a farnesyl:protein transferase inhibitor.
Omer CA, Chen Z, Diehl RE, Conner MW, Chen HY, Trumbauer ME, Gopal-Truter S, Seeburger G, Bhimnathwala H, Abrams MT, Davide JP, Ellis MS, Gibbs JB, Greenberg I, Koblan KS, Kral AM, Liu D, Lobell RB, Miller PJ, Mosser SD, O'Neill TJ, Rands E, Schaber MD, Senderak ET, Oliff A, Kohl NE. Omer CA, et al. Among authors: oliff a. Cancer Res. 2000 May 15;60(10):2680-8. Cancer Res. 2000. PMID: 10825141
Pseudodipeptide inhibitors of protein farnesyltransferase.
deSolms SJ, Deana AA, Giuliani EA, Graham SL, Kohl NE, Mosser SD, Oliff AI, Pompliano DL, Rands E, Scholz TH, et al. deSolms SJ, et al. Among authors: oliff ai. J Med Chem. 1995 Sep 29;38(20):3967-71. doi: 10.1021/jm00020a010. J Med Chem. 1995. PMID: 7562930
130 results