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Identification and manipulation of biliary metaplasia in pancreatic tumors.
Delgiorno KE, Hall JC, Takeuchi KK, Pan FC, Halbrook CJ, Washington MK, Olive KP, Spence JR, Sipos B, Wright CV, Wells JM, Crawford HC. Delgiorno KE, et al. Among authors: olive kp. Gastroenterology. 2014 Jan;146(1):233-44.e5. doi: 10.1053/j.gastro.2013.08.053. Epub 2013 Aug 30. Gastroenterology. 2014. PMID: 23999170 Free PMC article.
Genetically engineered mouse models of pancreatic cancer.
Westphalen CB, Olive KP. Westphalen CB, et al. Among authors: olive kp. Cancer J. 2012 Nov-Dec;18(6):502-10. doi: 10.1097/PPO.0b013e31827ab4c4. Cancer J. 2012. PMID: 23187836 Free PMC article. Review.
Bmi1 is required for the initiation of pancreatic cancer through an Ink4a-independent mechanism.
Bednar F, Schofield HK, Collins MA, Yan W, Zhang Y, Shyam N, Eberle JA, Almada LL, Olive KP, Bardeesy N, Fernandez-Zapico ME, Nakada D, Simeone DM, Morrison SJ, Pasca di Magliano M. Bednar F, et al. Among authors: olive kp. Carcinogenesis. 2015 Jul;36(7):730-8. doi: 10.1093/carcin/bgv058. Epub 2015 May 4. Carcinogenesis. 2015. PMID: 25939753 Free PMC article.
Cholinergic Signaling via Muscarinic Receptors Directly and Indirectly Suppresses Pancreatic Tumorigenesis and Cancer Stemness.
Renz BW, Tanaka T, Sunagawa M, Takahashi R, Jiang Z, Macchini M, Dantes Z, Valenti G, White RA, Middelhoff MA, Ilmer M, Oberstein PE, Angele MK, Deng H, Hayakawa Y, Westphalen CB, Werner J, Remotti H, Reichert M, Tailor YH, Nagar K, Friedman RA, Iuga AC, Olive KP, Wang TC. Renz BW, et al. Among authors: olive kp. Cancer Discov. 2018 Nov;8(11):1458-1473. doi: 10.1158/2159-8290.CD-18-0046. Epub 2018 Sep 5. Cancer Discov. 2018. PMID: 30185628 Free PMC article.
Cysteine depletion induces pancreatic tumor ferroptosis in mice.
Badgley MA, Kremer DM, Maurer HC, DelGiorno KE, Lee HJ, Purohit V, Sagalovskiy IR, Ma A, Kapilian J, Firl CEM, Decker AR, Sastra SA, Palermo CF, Andrade LR, Sajjakulnukit P, Zhang L, Tolstyka ZP, Hirschhorn T, Lamb C, Liu T, Gu W, Seeley ES, Stone E, Georgiou G, Manor U, Iuga A, Wahl GM, Stockwell BR, Lyssiotis CA, Olive KP. Badgley MA, et al. Among authors: olive kp. Science. 2020 Apr 3;368(6486):85-89. doi: 10.1126/science.aaw9872. Science. 2020. PMID: 32241947 Free PMC article.
Tuft Cells Inhibit Pancreatic Tumorigenesis in Mice by Producing Prostaglandin D2.
DelGiorno KE, Chung CY, Vavinskaya V, Maurer HC, Novak SW, Lytle NK, Ma Z, Giraddi RR, Wang D, Fang L, Naeem RF, Andrade LR, Ali WH, Tseng H, Tsui C, Gubbala VB, Ridinger-Saison M, Ohmoto M, Erikson GA, O'Connor C, Shokhirev MN, Hah N, Urade Y, Matsumoto I, Kaech SM, Singh PK, Manor U, Olive KP, Wahl GM. DelGiorno KE, et al. Among authors: olive kp. Gastroenterology. 2020 Nov;159(5):1866-1881.e8. doi: 10.1053/j.gastro.2020.07.037. Epub 2020 Jul 24. Gastroenterology. 2020. PMID: 32717220 Free PMC article.
GOT1 inhibition promotes pancreatic cancer cell death by ferroptosis.
Kremer DM, Nelson BS, Lin L, Yarosz EL, Halbrook CJ, Kerk SA, Sajjakulnukit P, Myers A, Thurston G, Hou SW, Carpenter ES, Andren AC, Nwosu ZC, Cusmano N, Wisner S, Mbah NE, Shan M, Das NK, Magnuson B, Little AC, Savani MR, Ramos J, Gao T, Sastra SA, Palermo CF, Badgley MA, Zhang L, Asara JM, McBrayer SK, di Magliano MP, Crawford HC, Shah YM, Olive KP, Lyssiotis CA. Kremer DM, et al. Among authors: olive kp. Nat Commun. 2021 Aug 11;12(1):4860. doi: 10.1038/s41467-021-24859-2. Nat Commun. 2021. PMID: 34381026 Free PMC article.
Enteroendocrine Cell Formation Is an Early Event in Pancreatic Tumorigenesis.
Caplan LR, Vavinskaya V, Gelikman DG, Jyotsana N, Trinh VQ, Olive KP, Tan MCB, DelGiorno KE. Caplan LR, et al. Among authors: olive kp. Front Physiol. 2022 Apr 27;13:865452. doi: 10.3389/fphys.2022.865452. eCollection 2022. Front Physiol. 2022. PMID: 35574446 Free PMC article.
Combinatorial Gli activity directs immune infiltration and tumor growth in pancreatic cancer.
Scales MK, Velez-Delgado A, Steele NG, Schrader HE, Stabnick AM, Yan W, Mercado Soto NM, Nwosu ZC, Johnson C, Zhang Y, Salas-Escabillas DJ, Menjivar RE, Maurer HC, Crawford HC, Bednar F, Olive KP, Pasca di Magliano M, Allen BL. Scales MK, et al. Among authors: olive kp. PLoS Genet. 2022 Jul 22;18(7):e1010315. doi: 10.1371/journal.pgen.1010315. eCollection 2022 Jul. PLoS Genet. 2022. PMID: 35867772 Free PMC article.
Eicosanoids in the pancreatic tumor microenvironment - a multicellular, multifaceted progression.
Gubbala VB, Jytosana N, Trinh VQ, Maurer HC, Naeem RF, Lytle NK, Ma Z, Zhao S, Lin W, Han H, Shi Y, Hunter T, Singh PK, Olive KP, Tan MCB, Kaech SM, Wahl GM, DelGiorno KE. Gubbala VB, et al. Among authors: olive kp. Gastro Hep Adv. 2022;1(4):682-697. doi: 10.1016/j.gastha.2022.02.007. Epub 2022 Jun 11. Gastro Hep Adv. 2022. PMID: 36277993 Free PMC article.
85 results