Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

My NCBI Filters
Text availability
Article attribute
Article type
Publication date

Search Results

1,396 results
Filters applied: . Clear all Results are displayed in a computed author sort order. Results by year timeline is unavailable
Page 1
The mismatch repair system (mutS, mutL and uvrD genes) in Pseudomonas aeruginosa: molecular characterization of naturally occurring mutants.
Oliver A, Baquero F, Blázquez J. Oliver A, et al. Mol Microbiol. 2002 Mar;43(6):1641-50. doi: 10.1046/j.1365-2958.2002.02855.x. Mol Microbiol. 2002. PMID: 11952911
The fourth mutS strain showed a 3.3 kb insertion after the 10th nucleotide of the mutS gene, and a 54 nucleotide deletion between two eight nucleotide direct repeats. ...The second mutL strain presented a K310M mutation, equivalent to K307 in Escherichia coli …
The fourth mutS strain showed a 3.3 kb insertion after the 10th nucleotide of the mutS gene, and a 54 nucleotide deletion betw …
Genes encoding TEM-4, SHV-2, and CTX-M-10 extended-spectrum beta-lactamases are carried by multiple Klebsiella pneumoniae clones in a single hospital (Madrid, 1989 to 2000).
Coque TM, Oliver A, Pérez-Díaz JC, Baquero F, Cantón R. Coque TM, et al. Antimicrob Agents Chemother. 2002 Feb;46(2):500-10. doi: 10.1128/aac.46.2.500-510.2002. Antimicrob Agents Chemother. 2002. PMID: 11796363 Free PMC article.
Only two of five K. pneumoniae TEM-4 clones caused more than a single case of infection, with one of them spreading for 9 months. ...Nevertheless, the spread of a single gene may be suggested by the presence of a conserved set of noncoding polymorphisms in th …
Only two of five K. pneumoniae TEM-4 clones caused more than a single case of infection, with one of them spreading for 9 months. ... …
Epidemiology of extended-spectrum beta-lactamase-producing Enterobacter isolates in a Spanish hospital during a 12-year period.
Cantón R, Oliver A, Coque TM, Varela Mdel C, Pérez-Díaz JC, Baquero F. Cantón R, et al. J Clin Microbiol. 2002 Apr;40(4):1237-43. doi: 10.1128/jcm.40.4.1237-1243.2002. J Clin Microbiol. 2002. PMID: 11923338 Free PMC article.
The remaining E. cloacae isolate harbored a TEM-27 ESBL, and the three E. aerogenes isolates harbored a TEM-24 ESBL. PFGE revealed that our E. aerogenes strain was indistinguishable from the French TEM-24-producing E. aerogenes endemic clone. Although a low p …
The remaining E. cloacae isolate harbored a TEM-27 ESBL, and the three E. aerogenes isolates harbored a TEM-24 ESBL. PFGE reve …
Mutation and evolution of antibiotic resistance: antibiotics as promoters of antibiotic resistance?
Blázquez J, Oliver A, Gómez-Gómez JM. Blázquez J, et al. Curr Drug Targets. 2002 Aug;3(4):345-9. doi: 10.2174/1389450023347579. Curr Drug Targets. 2002. PMID: 12102604 Review.
Antibiotic resistance appearance and spread have been classically considered the result of a process of natural selection, directed by the use of antibiotics. ...Here, we present a review of the last data on molecular mechanisms of hypermutability in bacteria and th …
Antibiotic resistance appearance and spread have been classically considered the result of a process of natural selection, directed b …
Characterization of the GO system of Pseudomonas aeruginosa.
Oliver A, Sánchez JM, Blázquez J. Oliver A, et al. FEMS Microbiol Lett. 2002 Nov 19;217(1):31-5. doi: 10.1111/j.1574-6968.2002.tb11452.x. FEMS Microbiol Lett. 2002. PMID: 12445642
The three genes, when cloned in a plasmid, were able to complement the high mutation frequency of the corresponding Escherichia coli deficient strains. ...In addition, the sequence of the P. aeruginosa mutT gene strongly suggested that the product of this gene has a
The three genes, when cloned in a plasmid, were able to complement the high mutation frequency of the corresponding Escherichia coli …
Lack of association between hypermutation and antibiotic resistance development in Pseudomonas aeruginosa isolates from intensive care unit patients.
Gutiérrez O, Juan C, Pérez JL, Oliver A. Gutiérrez O, et al. Antimicrob Agents Chemother. 2004 Sep;48(9):3573-5. doi: 10.1128/AAC.48.9.3573-3575.2004. Antimicrob Agents Chemother. 2004. PMID: 15328130 Free PMC article.
Hypermutation is a common feature of Pseudomonas aeruginosa isolates from chronically infected cystic fibrosis patients that is linked with antibiotic resistance development. In this work, using a large collection of sequential P. aeruginosa isolates from ICU patien …
Hypermutation is a common feature of Pseudomonas aeruginosa isolates from chronically infected cystic fibrosis patients that is linke …
Hypermutation and the preexistence of antibiotic-resistant Pseudomonas aeruginosa mutants: implications for susceptibility testing and treatment of chronic infections.
Oliver A, Levin BR, Juan C, Baquero F, Blázquez J. Oliver A, et al. Antimicrob Agents Chemother. 2004 Nov;48(11):4226-33. doi: 10.1128/AAC.48.11.4226-4233.2004. Antimicrob Agents Chemother. 2004. PMID: 15504845 Free PMC article.
In the present investigation, we argue that for the treatment of chronic infections caused by hypermutable Pseudomonas aeruginosa of the sort frequently found in cystic fibrosis patients, mutants resistant to all single antipseudomonal drugs will almost invariably be present in …
In the present investigation, we argue that for the treatment of chronic infections caused by hypermutable Pseudomonas aeruginosa of the sor …
Characterization of a large outbreak by CTX-M-1-producing Klebsiella pneumoniae and mechanisms leading to in vivo carbapenem resistance development.
Mena A, Plasencia V, García L, Hidalgo O, Ayestarán JI, Alberti S, Borrell N, Pérez JL, Oliver A. Mena A, et al. J Clin Microbiol. 2006 Aug;44(8):2831-7. doi: 10.1128/JCM.00418-06. J Clin Microbiol. 2006. PMID: 16891499 Free PMC article.
CTX-M-1 as well as the aminoglycoside resistance determinants were encoded in a 50-kb plasmid that could be transferred to Escherichia coli only by transformation. ...This is the first report of a large outbreak of CTX-M-1-producing Enterobacteriaceae and, curiously …
CTX-M-1 as well as the aminoglycoside resistance determinants were encoded in a 50-kb plasmid that could be transferred to Escherichi …
Benefit of having multiple ampD genes for acquiring beta-lactam resistance without losing fitness and virulence in Pseudomonas aeruginosa.
Moya B, Juan C, Albertí S, Pérez JL, Oliver A. Moya B, et al. Antimicrob Agents Chemother. 2008 Oct;52(10):3694-700. doi: 10.1128/AAC.00172-08. Epub 2008 Jul 21. Antimicrob Agents Chemother. 2008. PMID: 18644952 Free PMC article.
The inactivation of ampD in Pseudomonas aeruginosa leads to a partially derepressed phenotype, characterized by a moderately high level basal ampC expression that is still further inducible, due to the presence of two additional ampD genes in this species (ampDh2 an …
The inactivation of ampD in Pseudomonas aeruginosa leads to a partially derepressed phenotype, characterized by a moderately h …
Beta-lactam resistance response triggered by inactivation of a nonessential penicillin-binding protein.
Moya B, Dötsch A, Juan C, Blázquez J, Zamorano L, Haussler S, Oliver A. Moya B, et al. PLoS Pathog. 2009 Mar;5(3):e1000353. doi: 10.1371/journal.ppat.1000353. Epub 2009 Mar 27. PLoS Pathog. 2009. PMID: 19325877 Free PMC article.
Using as a model Pseudomonas aeruginosa, high up on the list of pathogens causing life-threatening infections in hospitalized patients worldwide, we show that PBPs may also play a major role in beta-lactam resistance in GNR, but through a totally distinct mec …
Using as a model Pseudomonas aeruginosa, high up on the list of pathogens causing life-threatening infections in hospitalized patient …
1,396 results
Jump to page
Feedback