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Mutators in cystic fibrosis chronic lung infection: Prevalence, mechanisms, and consequences for antimicrobial therapy.
Oliver A. Oliver A. Int J Med Microbiol. 2010 Dec;300(8):563-72. doi: 10.1016/j.ijmm.2010.08.009. Epub 2010 Sep 15. Int J Med Microbiol. 2010. PMID: 20837399 Review.
Over last decade, several studies have provided strong evidence of a relevant role of mutators in the evolution of natural bacterial populations, with a special emphasis in the field of infectious diseases. ...Further prospective clinical studies are nevertheless ne …
Over last decade, several studies have provided strong evidence of a relevant role of mutators in the evolution of natural bacterial …
Evaluation of the Wider system, a new computer-assisted image-processing device for bacterial identification and susceptibility testing.
Cantón R, Pérez-Vázquez M, Oliver A, Sánchez Del Saz B, Gutiérrez MO, Martínez-Ferrer M, Baquero F. Cantón R, et al. J Clin Microbiol. 2000 Apr;38(4):1339-46. doi: 10.1128/JCM.38.4.1339-1346.2000. J Clin Microbiol. 2000. PMID: 10747104 Free PMC article.
The Wider system is a newly developed computer-assisted image-processing device for both bacterial identification and antimicrobial susceptibility testing. ...The Wider system is a new reliable tool which applies the image-processing technology to the reading of com …
The Wider system is a newly developed computer-assisted image-processing device for both bacterial identification and antimicrobial s …
High frequency of hypermutable Pseudomonas aeruginosa in cystic fibrosis lung infection.
Oliver A, Cantón R, Campo P, Baquero F, Blázquez J. Oliver A, et al. Science. 2000 May 19;288(5469):1251-4. doi: 10.1126/science.288.5469.1251. Science. 2000. PMID: 10818002
The lungs of cystic fibrosis (CF) patients are chronically infected for years by one or a few lineages of Pseudomonas aeruginosa. ...This investigation also reveals a link between high mutation rates in vivo and the evolution of antibiotic resistance....
The lungs of cystic fibrosis (CF) patients are chronically infected for years by one or a few lineages of Pseudomonas aeruginosa. ... …
Nontuberculous mycobacteria in patients with cystic fibrosis.
Oliver A, Maiz L, Cantón R, Escobar H, Baquero F, Gómez-Mampaso E. Oliver A, et al. Clin Infect Dis. 2001 May 1;32(9):1298-303. doi: 10.1086/319987. Epub 2001 Apr 13. Clin Infect Dis. 2001. PMID: 11303264
An improvement in pulmonary function was observed in 2 patients after they received a course of antimycobacterial therapy. Screening for nontuberculous mycobacteria in patients with cystic fibrosis will contribute to understanding the relevance of these pathogens with rega …
An improvement in pulmonary function was observed in 2 patients after they received a course of antimycobacterial therapy. Screening …
[Multiresistant pathogens in cystic fibrosis].
Cantón R, Girón R, Martínez-Martínez L, Oliver A, Solé A, Valdezate S, Máiz L. Cantón R, et al. Arch Bronconeumol. 2002 Aug;38(8):376-85. doi: 10.1016/s0300-2896(02)75243-5. Arch Bronconeumol. 2002. PMID: 12199920 Review. Spanish. No abstract available.
Epidemiological relatedness of methicillin-resistant Staphylococcus aureus from a tertiary hospital and a geriatric institution in Spain.
Ruiz de Gopegui E, Oliver A, Ramírez A, Gutiérrez O, Andreu C, Pérez JL. Ruiz de Gopegui E, et al. Clin Microbiol Infect. 2004 Apr;10(4):339-42. doi: 10.1111/j.1198-743X.2004.00867.x. Clin Microbiol Infect. 2004. PMID: 15059126
From January 2000 to June 2002, 24 Staphylococcus aureus isolates were recovered from decubitus ulcers of patients in a geriatric institution, of which 17 (70.8%) were methicillin-resistant S. aureus (MRSA). Antibiotic resistance and DNA macrorestriction (pulsed-field gel …
From January 2000 to June 2002, 24 Staphylococcus aureus isolates were recovered from decubitus ulcers of patients in a geriatric ins …
Detection and susceptibility testing of hypermutable Pseudomonas aeruginosa strains with the Etest and disk diffusion.
Maciá MD, Borrell N, Pérez JL, Oliver A. Maciá MD, et al. Antimicrob Agents Chemother. 2004 Jul;48(7):2665-72. doi: 10.1128/AAC.48.7.2665-2672.2004. Antimicrob Agents Chemother. 2004. PMID: 15215124 Free PMC article.
Resistance development in Pseudomonas aeruginosa from chronically colonized cystic fibrosis (CF) patients has been linked to the presence of a high proportion of mismatch repair-deficient hypermutable strains. ...
Resistance development in Pseudomonas aeruginosa from chronically colonized cystic fibrosis (CF) patients has been linked to the presence of …
[Consolidation of a Staphylococcus aureus multiresistant clone not related to the Iberian in a hospital from Mallorca].
Ruiz de Gopegui E, Oliver A, Galmés MI, Hidalgo O, Pérez JL. Ruiz de Gopegui E, et al. Enferm Infecc Microbiol Clin. 2005 Mar;23(3):140-4. doi: 10.1157/13072163. Enferm Infecc Microbiol Clin. 2005. PMID: 15757585 Spanish.
Whereas the predominant clone in 1999 was clone A (clone A 63%, clone B 20%), clone B was now found to predominate (clone B 58%, clone A 19%). ...CONCLUSION: In recent years, a formerly predominant MRSA clone has been replaced by a multiresistan …
Whereas the predominant clone in 1999 was clone A (clone A 63%, clone B 20%), clone B was now found to predominate (clone B 58 …
Hypermutation is a key factor in development of multiple-antimicrobial resistance in Pseudomonas aeruginosa strains causing chronic lung infections.
Maciá MD, Blanquer D, Togores B, Sauleda J, Pérez JL, Oliver A. Maciá MD, et al. Antimicrob Agents Chemother. 2005 Aug;49(8):3382-6. doi: 10.1128/AAC.49.8.3382-3386.2005. Antimicrob Agents Chemother. 2005. PMID: 16048951 Free PMC article.
Hypermutable P. aeruginosa strains are extremely prevalent in chronic infections in contrast to what has been described in acute processes, suggesting a role of hypermutation in bacterial adaptation for long-term persistence. Furthermore, hypermutation is found to be a
Hypermutable P. aeruginosa strains are extremely prevalent in chronic infections in contrast to what has been described in acute processes, …
Antimicrobial therapy for pulmonary pathogenic colonisation and infection by Pseudomonas aeruginosa in cystic fibrosis patients.
Cantón R, Cobos N, de Gracia J, Baquero F, Honorato J, Gartner S, Alvarez A, Salcedo A, Oliver A, García-Quetglas E; Spanish Consensus Group for Antimicrobial Therapy in the Cystic Fibrosis Patient. Cantón R, et al. Clin Microbiol Infect. 2005 Sep;11(9):690-703. doi: 10.1111/j.1469-0691.2005.01217.x. Clin Microbiol Infect. 2005. PMID: 16104983 Review.
Pseudomonas aeruginosa colonisation has a negative effect on pulmonary function in cystic fibrosis patients. The organism can only be eradicated in the early stage of colonisation, while reduction of bacterial density is desirable during chronic colonisation or exacerbatio …
Pseudomonas aeruginosa colonisation has a negative effect on pulmonary function in cystic fibrosis patients. The organism can only be …
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