Overall, Stage 2 of Meaningful Use presents a series of opportunities and challenges for nephrologists. Make sure that you are prepared for the transition by 2014, if not sooner. Open a dialogue with your EHR vendor now to understand how they plan to support nephrologists in meeting the requirements of Stage 2, and read the resources available on the CMS website or through professional societies. With the right tools and strong support, we can meet the challenges in this next stage of Meaningful Use and take advantage of the opportunities facing us.