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Getting at the root and stem of brain tumors.
Oliver TG, Wechsler-Reya RJ. Oliver TG, et al. Neuron. 2004 Jun 24;42(6):885-8. doi: 10.1016/j.neuron.2004.06.011. Neuron. 2004. PMID: 15207233 Review.
Transcriptional profiling of the Sonic hedgehog response: a critical role for N-myc in proliferation of neuronal precursors.
Oliver TG, Grasfeder LL, Carroll AL, Kaiser C, Gillingham CL, Lin SM, Wickramasinghe R, Scott MP, Wechsler-Reya RJ. Oliver TG, et al. Proc Natl Acad Sci U S A. 2003 Jun 10;100(12):7331-6. doi: 10.1073/pnas.0832317100. Epub 2003 May 30. Proc Natl Acad Sci U S A. 2003. PMID: 12777630 Free PMC article.
Fibroblast growth factor blocks Sonic hedgehog signaling in neuronal precursors and tumor cells.
Fogarty MP, Emmenegger BA, Grasfeder LL, Oliver TG, Wechsler-Reya RJ. Fogarty MP, et al. Proc Natl Acad Sci U S A. 2007 Feb 20;104(8):2973-8. doi: 10.1073/pnas.0605770104. Epub 2007 Feb 13. Proc Natl Acad Sci U S A. 2007. PMID: 17299056 Free PMC article.
Suppression of Rev3, the catalytic subunit of Pol{zeta}, sensitizes drug-resistant lung tumors to chemotherapy.
Doles J, Oliver TG, Cameron ER, Hsu G, Jacks T, Walker GC, Hemann MT. Doles J, et al. Proc Natl Acad Sci U S A. 2010 Nov 30;107(48):20786-91. doi: 10.1073/pnas.1011409107. Epub 2010 Nov 10. Proc Natl Acad Sci U S A. 2010. PMID: 21068376 Free PMC article.
Chronic cisplatin treatment promotes enhanced damage repair and tumor progression in a mouse model of lung cancer.
Oliver TG, Mercer KL, Sayles LC, Burke JR, Mendus D, Lovejoy KS, Cheng MH, Subramanian A, Mu D, Powers S, Crowley D, Bronson RT, Whittaker CA, Bhutkar A, Lippard SJ, Golub T, Thomale J, Jacks T, Sweet-Cordero EA. Oliver TG, et al. Genes Dev. 2010 Apr 15;24(8):837-52. doi: 10.1101/gad.1897010. Genes Dev. 2010. PMID: 20395368 Free PMC article.
Caspase-2-mediated cleavage of Mdm2 creates a p53-induced positive feedback loop.
Oliver TG, Meylan E, Chang GP, Xue W, Burke JR, Humpton TJ, Hubbard D, Bhutkar A, Jacks T. Oliver TG, et al. Mol Cell. 2011 Jul 8;43(1):57-71. doi: 10.1016/j.molcel.2011.06.012. Mol Cell. 2011. PMID: 21726810 Free PMC article.
Pten-null tumors cohabiting the same lung display differential AKT activation and sensitivity to dietary restriction.
Curry NL, Mino-Kenudson M, Oliver TG, Yilmaz OH, Yilmaz VO, Moon JY, Jacks T, Sabatini DM, Kalaany NY. Curry NL, et al. Cancer Discov. 2013 Aug;3(8):908-21. doi: 10.1158/2159-8290.CD-12-0507. Epub 2013 May 29. Cancer Discov. 2013. PMID: 23719831 Free PMC article.
GLUT3 is induced during epithelial-mesenchymal transition and promotes tumor cell proliferation in non-small cell lung cancer.
Masin M, Vazquez J, Rossi S, Groeneveld S, Samson N, Schwalie PC, Deplancke B, Frawley LE, Gouttenoire J, Moradpour D, Oliver TG, Meylan E. Masin M, et al. Cancer Metab. 2014 Jul 29;2:11. doi: 10.1186/2049-3002-2-11. eCollection 2014. Cancer Metab. 2014. PMID: 25097756 Free PMC article.
Caspase-2 impacts lung tumorigenesis and chemotherapy response in vivo.
Terry MR, Arya R, Mukhopadhyay A, Berrett KC, Clair PM, Witt B, Salama ME, Bhutkar A, Oliver TG. Terry MR, et al. Cell Death Differ. 2015 May;22(5):719-30. doi: 10.1038/cdd.2014.159. Epub 2014 Oct 10. Cell Death Differ. 2015. PMID: 25301067 Free PMC article.
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