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The basic region of myogenin cooperates with two transcription activation domains to induce muscle-specific transcription.
Schwarz JJ, Chakraborty T, Martin J, Zhou JM, Olson EN. Schwarz JJ, et al. Mol Cell Biol. 1992 Jan;12(1):266-75. doi: 10.1128/mcb.12.1.266. Mol Cell Biol. 1992. PMID: 1309591 Free PMC article.
Activation of the myogenic program by myogenin is dependent on its binding to a DNA sequence known as an E box, which is associated with numerous muscle-specific genes. ...These transcription activation domains are dependent for activity on a specific amino acid sequence w …
Activation of the myogenic program by myogenin is dependent on its binding to a DNA sequence known as an E box, which is associated w …
Repression of myogenin function by TGF-beta 1 is targeted at the basic helix-loop-helix motif and is independent of E2A products.
Martin JF, Li L, Olson EN. Martin JF, et al. J Biol Chem. 1992 Jun 5;267(16):10956-60. J Biol Chem. 1992. PMID: 1317849
The muscle-specific helix-loop-helix (HLH) proteins myogenin, MyoD, myf5, and MRF4 form hetero-oligomers with ubiquitous HLH proteins encoded by the E2A gene and activate muscle transcription by binding to a DNA sequence known as an E-box (CANNTG). ...Using a series of rep …
The muscle-specific helix-loop-helix (HLH) proteins myogenin, MyoD, myf5, and MRF4 form hetero-oligomers with ubiquitous HLH proteins encode …
Analysis of the myogenin promoter reveals an indirect pathway for positive autoregulation mediated by the muscle-specific enhancer factor MEF-2.
Edmondson DG, Cheng TC, Cserjesi P, Chakraborty T, Olson EN. Edmondson DG, et al. Mol Cell Biol. 1992 Sep;12(9):3665-77. doi: 10.1128/mcb.12.9.3665. Mol Cell Biol. 1992. PMID: 1324403 Free PMC article.
Myogenin-directed transcription has been shown to occur through interaction with a DNA consensus sequence known as an E box (CANNTG) present in the control regions of numerous downstream genes. ...
Myogenin-directed transcription has been shown to occur through interaction with a DNA consensus sequence known as an E box (CANNTG) …
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