Olson SH - Search Results

1

Tau prions from Alzheimer's disease and chronic traumatic encephalopathy patients propagate in cultured cells.

Woerman AL, Aoyagi A, Patel S, Kazmi SA, Lobach I, Grinberg LT, McKee AC, Seeley WW, Olson SH, Prusiner SB. Woerman AL, et al. Among authors: olson sh. Proc Natl Acad Sci U S A. 2016 Dec 13;113(50):E8187-E8196. doi: 10.1073/pnas.1616344113. Epub 2016 Nov 28. Proc Natl Acad Sci U S A. 2016. PMID: 27911827 Free PMC article.

2

Optimization of Aryl Amides that Extend Survival in Prion-Infected Mice.

Giles K, Berry DB, Condello C, Dugger BN, Li Z, Oehler A, Bhardwaj S, Elepano M, Guan S, Silber BM, Olson SH, Prusiner SB. Giles K, et al. Among authors: olson sh. J Pharmacol Exp Ther. 2016 Sep;358(3):537-47. doi: 10.1124/jpet.116.235556. Epub 2016 Jun 17. J Pharmacol Exp Ther. 2016. PMID: 27317802 Free PMC article.

3

Developing Therapeutics for PrP Prion Diseases.

Giles K, Olson SH, Prusiner SB. Giles K, et al. Among authors: olson sh. Cold Spring Harb Perspect Med. 2017 Apr 3;7(4):a023747. doi: 10.1101/cshperspect.a023747. Cold Spring Harb Perspect Med. 2017. PMID: 28096242 Free PMC article. Review.

4

MSA prions exhibit remarkable stability and resistance to inactivation.

Woerman AL, Kazmi SA, Patel S, Freyman Y, Oehler A, Aoyagi A, Mordes DA, Halliday GM, Middleton LT, Gentleman SM, Olson SH, Prusiner SB. Woerman AL, et al. Among authors: olson sh. Acta Neuropathol. 2018 Jan;135(1):49-63. doi: 10.1007/s00401-017-1762-2. Epub 2017 Aug 28. Acta Neuropathol. 2018. PMID: 28849371 Free PMC article.

5

Kinetics of Human Mutant Tau Prion Formation in the Brains of 2 Transgenic Mouse Lines.

Woerman AL, Patel S, Kazmi SA, Oehler A, Freyman Y, Espiritu L, Cotter R, Castaneda JA, Olson SH, Prusiner SB. Woerman AL, et al. Among authors: olson sh. JAMA Neurol. 2017 Dec 1;74(12):1464-1472. doi: 10.1001/jamaneurol.2017.2822. JAMA Neurol. 2017. PMID: 29059326 Free PMC article.

6

Familial Parkinson's point mutation abolishes multiple system atrophy prion replication.

Woerman AL, Kazmi SA, Patel S, Aoyagi A, Oehler A, Widjaja K, Mordes DA, Olson SH, Prusiner SB. Woerman AL, et al. Among authors: olson sh. Proc Natl Acad Sci U S A. 2018 Jan 9;115(2):409-414. doi: 10.1073/pnas.1719369115. Epub 2017 Dec 26. Proc Natl Acad Sci U S A. 2018. PMID: 29279394 Free PMC article.

7

Multiple system atrophy prions retain strain specificity after serial propagation in two different Tg(SNCA*A53T) mouse lines.

Woerman AL, Oehler A, Kazmi SA, Lee J, Halliday GM, Middleton LT, Gentleman SM, Mordes DA, Spina S, Grinberg LT, Olson SH, Prusiner SB. Woerman AL, et al. Among authors: olson sh. Acta Neuropathol. 2019 Mar;137(3):437-454. doi: 10.1007/s00401-019-01959-4. Epub 2019 Jan 28. Acta Neuropathol. 2019. PMID: 30690664 Free PMC article.

8

Kinetics of α-synuclein prions preceding neuropathological inclusions in multiple system atrophy.

Woerman AL, Patel S, Kazmi SA, Oehler A, Lee J, Mordes DA, Olson SH, Prusiner SB. Woerman AL, et al. Among authors: olson sh. PLoS Pathog. 2020 Feb 4;16(2):e1008222. doi: 10.1371/journal.ppat.1008222. eCollection 2020 Feb. PLoS Pathog. 2020. PMID: 32017806 Free PMC article.

9

Discovery of 4-Piperazine Isoquinoline Derivatives as Potent and Brain-Permeable Tau Prion Inhibitors with CDK8 Activity.

Grandjean JM, Jiu AY, West JW, Aoyagi A, Droege DG, Elepano M, Hirasawa M, Hirouchi M, Murakami R, Lee J, Sasaki K, Hirano S, Ohyama T, Tang BC, Vaz RJ, Inoue M, Olson SH, Prusiner SB, Conrad J, Paras NA. Grandjean JM, et al. Among authors: olson sh. ACS Med Chem Lett. 2020 Jan 30;11(2):127-132. doi: 10.1021/acsmedchemlett.9b00480. eCollection 2020 Feb 13. ACS Med Chem Lett. 2020. PMID: 32071678 Free PMC article.

10

Water-Soluble Iridium Photoredox Catalyst for the Trifluoromethylation of Biomolecule Substrates in Phosphate Buffered Saline Solvent.

Nguyen TH, O'Brien CJ, Tran MLN, Olson SH, Settineri NS, Prusiner SB, Paras NA, Conrad J. Nguyen TH, et al. Among authors: olson sh. Org Lett. 2021 May 21;23(10):3823-3827. doi: 10.1021/acs.orglett.1c00871. Epub 2021 Apr 30. Org Lett. 2021. PMID: 33929208

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