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A novel nitric oxide releasing prostaglandin analog, NCX 125, reduces intraocular pressure in rabbit, dog, and primate models of glaucoma.
Borghi V, Bastia E, Guzzetta M, Chiroli V, Toris CB, Batugo MR, Carreiro ST, Chong WK, Gale DC, Kucera DJ, Jia L, Prasanna G, Ongini E, Krauss AH, Impagnatiello F. Borghi V, et al. J Ocul Pharmacol Ther. 2010 Apr;26(2):125-32. doi: 10.1089/jop.2009.0120. J Ocul Pharmacol Ther. 2010. PMID: 20415621
Nociceptin and the ORL-1 ligand [Phe1psi (CH2-NH)Gly2]nociceptin(1-13)NH2 exert anti-opioid effects in the Freund's adjuvant-induced arthritic rat model of chronic pain.
Bertorelli R, Corradini L, Rafiq K, Tupper J, Calò G, Ongini E. Bertorelli R, et al. Br J Pharmacol. 1999 Nov;128(6):1252-8. doi: 10.1038/sj.bjp.0702884. Br J Pharmacol. 1999. PMID: 10578139 Free PMC article.
Comparison of CGS 15943, ZM 241385 and SCH 58261 as antagonists at human adenosine receptors.
Ongini E, Dionisotti S, Gessi S, Irenius E, Fredholm BB. Ongini E, et al. Naunyn Schmiedebergs Arch Pharmacol. 1999 Jan;359(1):7-10. doi: 10.1007/pl00005326. Naunyn Schmiedebergs Arch Pharmacol. 1999. PMID: 9933143
Spirapril prevents left ventricular hypertrophy, decreases myocardial damage and promotes angiogenesis in spontaneously hypertensive rats.
Olivetti G, Cigola E, Lagrasta C, Ricci R, Quaini F, Monopoli A, Ongini E. Olivetti G, et al. J Cardiovasc Pharmacol. 1993 Mar;21(3):362-70. doi: 10.1097/00005344-199303000-00003. J Cardiovasc Pharmacol. 1993. PMID: 7681495
Anticonvulsant doses of 2-chloro-N6-cyclopentyladenosine, an adenosine A1 receptor agonist, reduce GABAergic transmission in different areas of the mouse brain.
Concas A, Santoro G, Mascia MP, Maciocco E, Dazzi L, Ongini E, Biggio G. Concas A, et al. J Pharmacol Exp Ther. 1993 Nov;267(2):844-51. J Pharmacol Exp Ther. 1993. PMID: 8246158
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