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Silibinin activated p53 and induced autophagic death in human fibrosarcoma HT1080 cells via reactive oxygen species-p38 and c-Jun N-terminal kinase pathways.
Duan WJ, Li QS, Xia MY, Tashiro S, Onodera S, Ikejima T. Duan WJ, et al. Biol Pharm Bull. 2011;34(1):47-53. doi: 10.1248/bpb.34.47. Biol Pharm Bull. 2011. PMID: 21212516
Pifithrin-α (PFT-α), a specific inhibitor of p53, reduced autophagy and reversed silibinin's growth-inhibitory effect; besides, PFT-α decreased the activation of caspase-3, a crucial executor of apoptosis. ...PD98059 (inhibitor of mitogen-activated protein kinase kinase (M …
Pifithrin-α (PFT-α), a specific inhibitor of p53, reduced autophagy and reversed silibinin's growth-inhibitory effect; besides, PFT-α …
Effects of liver-supplemented food on the development of embryos in mice.
Akase T, Yamashina S, Akase T, Onodera S, Okuda H, Tashiro S. Akase T, et al. Biol Pharm Bull. 2003 Apr;26(4):553-6. doi: 10.1248/bpb.26.553. Biol Pharm Bull. 2003. PMID: 12673043
Intracellular regulation of evodiamine-induced A375-S2 cell death.
Zhang Y, Wu LJ, Tashiro S, Onodera S, Ikejima T. Zhang Y, et al. Biol Pharm Bull. 2003 Nov;26(11):1543-7. doi: 10.1248/bpb.26.1543. Biol Pharm Bull. 2003. PMID: 14600398
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