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[Pollution level during inhalation sedation with a 50%N2O/50%O2 premix: comparison of two administration devices].
Hennequin M, Onody P. Hennequin M, et al. Ann Fr Anesth Reanim. 2004 Oct;23(10):959-65. doi: 10.1016/j.annfar.2004.08.007. Ann Fr Anesth Reanim. 2004. PMID: 15501625 French.
RESULTS: The mean TWA calculated for the two evolution periods was significantly lower with the on-demand system than where compared the continuous flow system (respectively 15.3 +/-23.1 and 32.3 +/-25.1 ppm; p < 0.05). ...
RESULTS: The mean TWA calculated for the two evolution periods was significantly lower with the on-demand system than where compared the con …
Modification of behavior with 50% nitrous oxide/oxygen conscious sedation over repeated visits for dental treatment a 3-year prospective study.
Collado V, Hennequin M, Faulks D, Mazille MN, Nicolas E, Koscielny S, Onody P. Collado V, et al. J Clin Psychopharmacol. 2006 Oct;26(5):474-81. doi: 10.1097/01.jcp.0000236660.01039.eb. J Clin Psychopharmacol. 2006. PMID: 16974188
Patient cooperation significantly improved during visits at first contact with the dentist and when applying the mask (P < 0.0001, between sessions 1 and 2). ...

Patient cooperation significantly improved during visits at first contact with the dentist and when applying the mask (P < 0.0001,

A clinical trial of efficacy and safety of inhalation sedation with a 50% nitrous oxide/oxygen premix (Kalinox™) in general practice.
Hennequin M, Collado V, Faulks D, Koscielny S, Onody P, Nicolas E. Hennequin M, et al. Clin Oral Investig. 2012 Apr;16(2):633-42. doi: 10.1007/s00784-011-0550-y. Epub 2011 Mar 29. Clin Oral Investig. 2012. PMID: 22186944 Clinical Trial.
Equimolar nitrous oxide/oxygen versus placebo for procedural pain in children: a randomized trial.
Reinoso-Barbero F, Pascual-Pascual SI, de Lucas R, García S, Billoët C, Dequenne V, Onody P. Reinoso-Barbero F, et al. Pediatrics. 2011 Jun;127(6):e1464-70. doi: 10.1542/peds.2010-1142. Epub 2011 May 23. Pediatrics. 2011. PMID: 21606149 Clinical Trial.

Patients not receiving EMONO (P = .0208)-in particular those aged younger than 3 years (P < .0001)-required more rescue analgesia. There were also significant differences between the 2 groups (EMONO versus placebo) for adequate collaboration (80% vs 35%; P

Patients not receiving EMONO (P = .0208)-in particular those aged younger than 3 years (P < .0001)-required more rescue ana

Evaluation of safe and effective administration of nitrous oxide after a postgraduate training course.
Collado V, Nicolas E, Faulks D, Tardieu C, Manière MC, Droz D, Onody P, Hennequin M. Collado V, et al. BMC Clin Pharmacol. 2008 Jun 11;8:3. doi: 10.1186/1472-6904-8-3. BMC Clin Pharmacol. 2008. PMID: 18547418 Free PMC article.

Trainees were less successful than experts for patients with intellectual disability (87.4% vs 94.2%, p < 0.01). For both groups, the degree of cooperation improved between initial induction and each perioperative step (Wilcoxon test, p < 0.01). However, for t

Trainees were less successful than experts for patients with intellectual disability (87.4% vs 94.2%, p < 0.01). For both groups,

Sedation with 50% nitrous oxide/oxygen for outpatient dental treatment in individuals with intellectual disability.
Faulks D, Hennequin M, Albecker-Grappe S, Manière MC, Tardieu C, Berthet A, Wolikow M, Droz D, Koscielny S, Onody P. Faulks D, et al. Dev Med Child Neurol. 2007 Aug;49(8):621-5. doi: 10.1111/j.1469-8749.2007.00621.x. Dev Med Child Neurol. 2007. PMID: 17635209 Clinical Trial.
The efficacy of premixed nitrous oxide and oxygen for fiberoptic bronchoscopy in pediatric patients: a randomized, double-blind, controlled study.
Fauroux B, Onody P, Gall O, Tourniaire B, Koscielny S, Clément A. Fauroux B, et al. Chest. 2004 Jan;125(1):315-21. doi: 10.1378/chest.125.1.315. Chest. 2004. PMID: 14718459 Clinical Trial.
MEASUREMENT AND RESULTS: The rate of failure was significantly greater in the control group (62%) than in the nitrous oxide group (21%, p = 0.00003). The efficacy of premixed 50% nitrous oxide and oxygen was also demonstrated with higher satisfaction scores (p = 0.0 …
MEASUREMENT AND RESULTS: The rate of failure was significantly greater in the control group (62%) than in the nitrous oxide group (21%, p
Prefixed equimolar nitrous oxide and oxygen mixture reduces discomfort during flexible bronchoscopy in adult patients: a randomized, controlled, double-blind trial.
Atassi K, Mangiapan G, Fuhrman C, Lasry S, Onody P, Housset B. Atassi K, et al. Chest. 2005 Aug;128(2):863-8. doi: 10.1378/chest.128.2.863. Chest. 2005. PMID: 16100179 Clinical Trial.
RESULTS: A significant increase in BP was observed only in the control group (p = 0.003), while pulse rate values did not differ between the two groups. As assessed by the VAS, pain was lower in the N2O group as compared to placebo (p = 0.02). Nose pain and cough we …
RESULTS: A significant increase in BP was observed only in the control group (p = 0.003), while pulse rate values did not differ betw …
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