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Efficacy of extract from Ononis spinosa L. on ethanol-induced gastric ulcer in rats.
Manal Ahmad A, Yasser Ibrahim K, Manal Mohammad A. Manal Ahmad A, et al. J Tradit Chin Med. 2021 Apr;41(2):270-275. J Tradit Chin Med. 2021. PMID: 33825407
OBJECTIVE: To investigate the efficacy of the extract from Ononis spinosa L. (O. spinosa) on ethanol-induced gastric ulcer in rats. METHODS: Phytochemical constituents of the extract from O. spinosa were analyzed using liquid chromatography-mass …
OBJECTIVE: To investigate the efficacy of the extract from Ononis spinosa L. (O. spinosa) on ethanol-induced gas …
Ononis spinosa L., an edible and medicinal plant: UHPLC-LTQ-Orbitrap/MS chemical profiling and biological activities of the herbal extract.
Stojković D , Drakulić D , Gašić U , Zengin G , Stevanović M , Rajčević N , Soković M . Stojković D , et al. Food Funct. 2020 Aug 1;11(8):7138-7151. doi: 10.1039/d0fo01595d. Epub 2020 Aug 4. Food Funct. 2020. PMID: 32749435
This study explored the chemical profile of the aerial parts of Ononis spinosa and further investigated its biological activities. Chemical profiling of the extract revealed the presence of 63 different compounds: phenolic acids, flavonoid glycosides and aglycones, …
This study explored the chemical profile of the aerial parts of Ononis spinosa and further investigated its biological activit …
Methanolic Extract of the Herb Ononis spinosa L. Is an Antifungal Agent with no Cytotoxicity to Primary Human Cells.
Stojković D, Dias MI, Drakulić D, Barros L, Stevanović M, C F R Ferreira I, D Soković M. Stojković D, et al. Pharmaceuticals (Basel). 2020 Apr 24;13(4):78. doi: 10.3390/ph13040078. Pharmaceuticals (Basel). 2020. PMID: 32344670 Free PMC article.
Ononis spinosa L. is a plant traditionally used as folk remedy. There are numerous studies regarding chemical constituents and health beneficial properties of Ononidis Radix. The following study was designed to investigate chemical composition and antifungal
Ononis spinosa L. is a plant traditionally used as folk remedy. There are numerous studies regarding chemical constitue
Analgesic and hepatotoxic effects of Ononis spinosa L.
Yilmaz BS, Ozbek H, Citoğlu GS, Uğraş S, Bayram I, Erdoğan E. Yilmaz BS, et al. Phytother Res. 2006 Jun;20(6):500-3. doi: 10.1002/ptr.1891. Phytother Res. 2006. PMID: 16619345
The present study investigated the analgesic and hepatoprotective activities of a water extract of Ononis spinosa L. (OS) in mice. Analgesic activity was based on the pain thresholds measured with the tail-flick test before administration at 30, 90 and 150 mi …
The present study investigated the analgesic and hepatoprotective activities of a water extract of Ononis spinosa L. (O …
Separation and characterization of homopipecolic acid isoflavonoid ester derivatives isolated from Ononis spinosa L. root.
Gampe N, Darcsi A, Kursinszki L, Béni S. Gampe N, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2018 Aug 1;1091:21-28. doi: 10.1016/j.jchromb.2018.05.023. Epub 2018 May 17. J Chromatogr B Analyt Technol Biomed Life Sci. 2018. PMID: 29803686
Spiny restharrow root (Ononis spinosa L.) and its preparations are mainly used for the treatment of urinary infections or bladder stones in numerous countries. ...
Spiny restharrow root (Ononis spinosa L.) and its preparations are mainly used for the treatment of urinary infections …
Isoflavonoids with inhibiting effects on human hyaluronidase-1 and norneolignan clitorienolactone B from Ononis spinosa L. root extract.
Addotey JN, Lengers I, Jose J, Gampe N, Béni S, Petereit F, Hensel A. Addotey JN, et al. Fitoterapia. 2018 Oct;130:169-174. doi: 10.1016/j.fitote.2018.08.013. Epub 2018 Sep 1. Fitoterapia. 2018. PMID: 30176279
Based on the traditional use of extracts from the roots from Ononis spinosa L. (Restharrow root) as a weak diuretic to achieve flushing of the urinary tract and as an adjuvant in minor urinary complaints the herbal material was selected for bioactivity guided …
Based on the traditional use of extracts from the roots from Ononis spinosa L. (Restharrow root) as a weak diuretic to …
Isolation of trifolirhizin from Ononis spinosa L.
Fujise Y, Toda T, Itô S. Fujise Y, et al. Chem Pharm Bull (Tokyo). 1965 Jan;13(1):93-5. doi: 10.1248/cpb.13.93. Chem Pharm Bull (Tokyo). 1965. PMID: 5864291 No abstract available.
Characterization and identification of isoflavonoid glycosides in the root of Spiny restharrow (Ononis spinosa L.) by HPLC-QTOF-MS, HPLC-MS/MS and NMR.
Gampe N, Darcsi A, Lohner S, Béni S, Kursinszki L. Gampe N, et al. J Pharm Biomed Anal. 2016 May 10;123:74-81. doi: 10.1016/j.jpba.2016.01.058. Epub 2016 Feb 2. J Pharm Biomed Anal. 2016. PMID: 26874257
The aim of our work was to perform a detailed structural characterization of the complete isoflavonoid profile in the aqueous-methanolic extract of Ononis spinosa root by high-performance liquid chromatography coupled with electrospray ionization accurate-mass quadr …
The aim of our work was to perform a detailed structural characterization of the complete isoflavonoid profile in the aqueous-methanolic ext …
Quantitative determination of isoflavonoids in Ononis species by UPLC-UV-DAD.
Gampe N, Nagy E, Kursinszki L, Béni S. Gampe N, et al. Phytochem Anal. 2021 Jul;32(4):474-481. doi: 10.1002/pca.2995. Epub 2020 Sep 14. Phytochem Anal. 2021. PMID: 32929804
INTRODUCTION: The root of the Ononis species has been used internally and externally in ethnomedicine for centuries and contains biologically valuable isoflavonoid compounds. ...OBJECTIVES: In this article we aimed to develop an optimised sample preparation protocol alongs …
INTRODUCTION: The root of the Ononis species has been used internally and externally in ethnomedicine for centuries and contains biol …
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