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A New Class of Safe Oligosaccharide Polymer Therapy To Modify the Mucus Barrier of Chronic Respiratory Disease.
Pritchard MF, Powell LC, Menzies GE, Lewis PD, Hawkins K, Wright C, Doull I, Walsh TR, Onsøyen E, Dessen A, Myrvold R, Rye PD, Myrset AH, Stevens HN, Hodges LA, MacGregor G, Neilly JB, Hill KE, Thomas DW. Pritchard MF, et al. Among authors: Onsoyen E. Mol Pharm. 2016 Mar 7;13(3):863-72. doi: 10.1021/acs.molpharmaceut.5b00794. Epub 2016 Feb 16. Mol Pharm. 2016. PMID: 26833139
Alginate oligosaccharides inhibit fungal cell growth and potentiate the activity of antifungals against Candida and Aspergillus spp.
Tøndervik A, Sletta H, Klinkenberg G, Emanuel C, Powell LC, Pritchard MF, Khan S, Craine KM, Onsøyen E, Rye PD, Wright C, Thomas DW, Hill KE. Tøndervik A, et al. Among authors: Onsoyen E. PLoS One. 2014 Nov 19;9(11):e112518. doi: 10.1371/journal.pone.0112518. eCollection 2014. PLoS One. 2014. PMID: 25409186 Free PMC article.
Overcoming drug resistance with alginate oligosaccharides able to potentiate the action of selected antibiotics.
Khan S, Tøndervik A, Sletta H, Klinkenberg G, Emanuel C, Onsøyen E, Myrvold R, Howe RA, Walsh TR, Hill KE, Thomas DW. Khan S, et al. Among authors: Onsoyen E. Antimicrob Agents Chemother. 2012 Oct;56(10):5134-41. doi: 10.1128/AAC.00525-12. Epub 2012 Jul 23. Antimicrob Agents Chemother. 2012. PMID: 22825116 Free PMC article.
An in vitro study of alginate oligomer therapies on oral biofilms.
Roberts JL, Khan S, Emanuel C, Powell LC, Pritchard MF, Onsøyen E, Myrvold R, Thomas DW, Hill KE. Roberts JL, et al. Among authors: Onsoyen E. J Dent. 2013 Oct;41(10):892-9. doi: 10.1016/j.jdent.2013.07.011. Epub 2013 Jul 30. J Dent. 2013. PMID: 23907083
OligoG CF-5/20 normalizes cystic fibrosis mucus by chelating calcium.
Ermund A, Recktenwald CV, Skjåk-Braek G, Meiss LN, Onsøyen E, Rye PD, Dessen A, Myrset AH, Hansson GC. Ermund A, et al. Among authors: Onsoyen E. Clin Exp Pharmacol Physiol. 2017 Jun;44(6):639-647. doi: 10.1111/1440-1681.12744. Clin Exp Pharmacol Physiol. 2017. PMID: 28261854
Alginate as a source of dietary fiber.
Brownlee IA, Allen A, Pearson JP, Dettmar PW, Havler ME, Atherton MR, Onsøyen E. Brownlee IA, et al. Among authors: Onsoyen E. Crit Rev Food Sci Nutr. 2005;45(6):497-510. doi: 10.1080/10408390500285673. Crit Rev Food Sci Nutr. 2005. PMID: 16183570 Review.
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