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Restricted immune activation and internalisation of anti-idiotype complexes between drug and antidrug antibodies.
van Schie KA, Kruithof S, Ooijevaar-de Heer P, Derksen NIL, van de Bovenkamp FS, Saris A, Vidarsson G, Bentlage AEH, Jiskoot W, Romeijn S, Koning RI, Bos E, Stork EM, Koeleman CAM, Wuhrer M, Wolbink G, Rispens T. van Schie KA, et al. Ann Rheum Dis. 2018 Oct;77(10):1471-1479. doi: 10.1136/annrheumdis-2018-213299. Epub 2018 Jun 26. Ann Rheum Dis. 2018. PMID: 29945923
Mechanism of immunoglobulin G4 Fab-arm exchange.
Rispens T, Ooijevaar-de Heer P, Bende O, Aalberse RC. Rispens T, et al. J Am Chem Soc. 2011 Jul 6;133(26):10302-11. doi: 10.1021/ja203638y. Epub 2011 Jun 15. J Am Chem Soc. 2011. PMID: 21627172
Drug interference in immunogenicity assays depends on valency.
Rispens T, Hart MH, Ooijevaar-de Heer P, van Leeuwen A, Vennegoor A, Killestein J, Wolbink GJ, van der Kleij D. Rispens T, et al. J Pharm Biomed Anal. 2013 Nov;85:179-85. doi: 10.1016/j.jpba.2013.07.022. Epub 2013 Jul 30. J Pharm Biomed Anal. 2013. PMID: 23954437
Structural determinants of unique properties of human IgG4-Fc.
Davies AM, Rispens T, Ooijevaar-de Heer P, Gould HJ, Jefferis R, Aalberse RC, Sutton BJ. Davies AM, et al. J Mol Biol. 2014 Feb 6;426(3):630-44. doi: 10.1016/j.jmb.2013.10.039. Epub 2013 Nov 6. J Mol Biol. 2014. PMID: 24211234 Free PMC article.
31 results