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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1959 1
1962 1
1963 1
1964 1
1974 1
1975 1
1979 2
1980 2
1981 2
1982 4
1984 1
1985 7
1986 7
1987 14
1988 57
1989 42
1990 66
1991 56
1992 67
1993 79
1994 58
1995 82
1996 98
1997 103
1998 124
1999 130
2000 155
2001 149
2002 143
2003 170
2004 164
2005 205
2006 215
2007 222
2008 254
2009 291
2010 315
2011 344
2012 392
2013 443
2014 665
2015 756
2016 746
2017 762
2018 838
2019 813
2020 900
2021 1005
2022 960
2023 962
2024 1271
2025 955

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13,406 results

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Page 1
Management of keratoconus: an updated review.
Deshmukh R, Ong ZZ, Rampat R, Alió Del Barrio JL, Barua A, Ang M, Mehta JS, Said DG, Dua HS, Ambrósio R Jr, Ting DSJ. Deshmukh R, et al. Front Med (Lausanne). 2023 Jun 20;10:1212314. doi: 10.3389/fmed.2023.1212314. eCollection 2023. Front Med (Lausanne). 2023. PMID: 37409272 Free PMC article. Review.
The treatment has expanded significantly from conservative management (e.g., spectacles and contact lenses wear) and penetrating keratoplasty to many other therapeutic and refractive modalities, including corneal cross-linking (with various protocols/techniques), combined …
The treatment has expanded significantly from conservative management (e.g., spectacles and contact lenses wear) and penetrating keratoplast …
Association Between Diabetes, Diabetic Retinopathy, and Glaucoma.
Li Y, Mitchell W, Elze T, Zebardast N. Li Y, et al. Curr Diab Rep. 2021 Sep 8;21(10):38. doi: 10.1007/s11892-021-01404-5. Curr Diab Rep. 2021. PMID: 34495413 Review.
We review evidence supporting and refuting this association and explore mechanistic pathological and treatment relationships linking these diseases. RECENT FINDINGS: While studies have shown diabetes/DR may increase the risk for glaucoma, this remains inconsistently demons …
We review evidence supporting and refuting this association and explore mechanistic pathological and treatment relationships linking …
Corneal cross-linking.
Hafezi F, Kling S, Hafezi NL, Aydemir ME, Lu NJ, Hillen M, Knyazer B, Awwad S, Mazzotta C, Kollros L, Torres-Netto EA. Hafezi F, et al. Prog Retin Eye Res. 2025 Jan;104:101322. doi: 10.1016/j.preteyeres.2024.101322. Epub 2024 Dec 15. Prog Retin Eye Res. 2025. PMID: 39681212 Review.
First introduced over 20 years ago as a treatment for progressive keratoconus, the original "Dresden" corneal cross-linking (CXL) protocol involved riboflavin saturation of the stroma, followed by 30 min of 3 mW/cm(2)-intensity ultraviolet-A (UV-A) irradiation. ...In PACK- …
First introduced over 20 years ago as a treatment for progressive keratoconus, the original "Dresden" corneal cross-linking (CXL) pro …
Refractive surgical correction and treatment of keratoconus.
D'Oria F, Bagaglia SA, Alio Del Barrio JL, Alessio G, Alio JL, Mazzotta C. D'Oria F, et al. Surv Ophthalmol. 2024 Jan-Feb;69(1):122-139. doi: 10.1016/j.survophthal.2023.09.005. Epub 2023 Sep 27. Surv Ophthalmol. 2024. PMID: 37774800 Free article. Review.
Paraneoplastic syndromes in ophthalmology.
Parrado-Carrillo A, Alcubierre R, Camós-Carreras A, Sanchez-Dalmau BF. Parrado-Carrillo A, et al. Arch Soc Esp Oftalmol (Engl Ed). 2022 Jun;97(6):350-357. doi: 10.1016/j.oftale.2022.03.006. Epub 2022 Mar 12. Arch Soc Esp Oftalmol (Engl Ed). 2022. PMID: 35292226 Review.
It is known that autoimmunity and autoantibody synthesis play an important role in its pathophysiology due to a process of molecular mimicry. Paraneoplastic syndromes in ophthalmology are rare, but it is important to recognize them clinically because in some cases symptoms …
It is known that autoimmunity and autoantibody synthesis play an important role in its pathophysiology due to a process of molecular mimicry …
Brillouin Spectroscopy in Ophthalmology.
Seiler TG, Geerling G. Seiler TG, et al. Klin Monbl Augenheilkd. 2023 Jun;240(6):779-782. doi: 10.1055/a-2085-5738. Epub 2023 May 4. Klin Monbl Augenheilkd. 2023. PMID: 37142238 Free article. Review. English, German.
Currently, available devices are able to detect focal corneal weakening, e.g., in keratoconus, as well as stiffening after corneal cross-linking. Also, the mechanical properties of the crystalline can be measured. Corneal anisotropy and hydration, together with the depende …
Currently, available devices are able to detect focal corneal weakening, e.g., in keratoconus, as well as stiffening after corneal cross- …
[Gene therapy in ophthalmology].
Priglinger CS, Gerhardt MJ, Rudolph G, Priglinger SG, Michalakis S. Priglinger CS, et al. Ophthalmologie. 2023 Aug;120(8):867-882. doi: 10.1007/s00347-023-01883-9. Epub 2023 Jul 7. Ophthalmologie. 2023. PMID: 37418021 Review. German.
The success of gene augmentation therapy in RPE65-linked retinal dystrophy encouraged research activities on the concept of gene supplementation to be extended to nongenetic diseases, such as age-related macular degeneration; however, it also showed that the principle of s …
The success of gene augmentation therapy in RPE65-linked retinal dystrophy encouraged research activities on the concept of gene supp …
Corneal cross-linking.
Randleman JB, Khandelwal SS, Hafezi F. Randleman JB, et al. Surv Ophthalmol. 2015 Nov-Dec;60(6):509-23. doi: 10.1016/j.survophthal.2015.04.002. Epub 2015 May 14. Surv Ophthalmol. 2015. PMID: 25980780 Review.
Since its inception in the late 1990s, corneal cross-linking has grown from an interesting concept to a primary treatment for corneal ectatic disease worldwide. ...We highlight the history of corneal cross-linking, the scientific underpinnings of current techniques, …
Since its inception in the late 1990s, corneal cross-linking has grown from an interesting concept to a primary treatment for corneal …
Keratoconus Treatment Algorithm.
Andreanos KD, Hashemi K, Petrelli M, Droutsas K, Georgalas I, Kymionis GD. Andreanos KD, et al. Ophthalmol Ther. 2017 Dec;6(2):245-262. doi: 10.1007/s40123-017-0099-1. Epub 2017 Jul 28. Ophthalmol Ther. 2017. PMID: 28755306 Free PMC article. Review.
The advent of new interventions such as cornea cross-linking, intrastromal corneal ring segments, and combined treatments provide corneal clinicians a variety of treatment options for the visual rehabilitation of keratoconus patients. ...
The advent of new interventions such as cornea cross-linking, intrastromal corneal ring segments, and combined treatments provide cor …
Individualized Corneal Cross-linking With Riboflavin and UV-A in Ultrathin Corneas: The Sub400 Protocol.
Hafezi F, Kling S, Gilardoni F, Hafezi N, Hillen M, Abrishamchi R, Gomes JAP, Mazzotta C, Randleman JB, Torres-Netto EA. Hafezi F, et al. Am J Ophthalmol. 2021 Apr;224:133-142. doi: 10.1016/j.ajo.2020.12.011. Epub 2021 Jan 30. Am J Ophthalmol. 2021. PMID: 33340508
PURPOSE: To determine whether corneal cross-linking (CXL) with individualized fluence ("sub400 protocol") is able to stop keratoconus (KC) progression in ultrathin corneas with 12-month follow-up. ...
PURPOSE: To determine whether corneal cross-linking (CXL) with individualized fluence ("sub400 protocol") is able to stop keratoconus …
13,406 results
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