Opoku-Nsiah K - Search Results

1

Biophysical determinants for cellular uptake of hydrocarbon-stapled peptide helices.

Bird GH, Mazzola E, Opoku-Nsiah K, Lammert MA, Godes M, Neuberg DS, Walensky LD. Bird GH, et al. Nat Chem Biol. 2016 Oct;12(10):845-52. doi: 10.1038/nchembio.2153. Epub 2016 Aug 22. Nat Chem Biol. 2016. PMID: 27547919 Free PMC article.

2

Hydrocarbon-Stitched Peptide Agonists of Glucagon-Like Peptide-1 Receptor.

Bird GH, Fu A, Escudero S, Godes M, Opoku-Nsiah K, Wales TE, Cameron MD, Engen JR, Danial NN, Walensky LD. Bird GH, et al. Among authors: opoku nsiah k. ACS Chem Biol. 2020 Jun 19;15(6):1340-1348. doi: 10.1021/acschembio.0c00308. Epub 2020 May 27. ACS Chem Biol. 2020. PMID: 32348108 Free PMC article.

3

Direct inhibition of oncogenic KRAS by hydrocarbon-stapled SOS1 helices.

Leshchiner ES, Parkhitko A, Bird GH, Luccarelli J, Bellairs JA, Escudero S, Opoku-Nsiah K, Godes M, Perrimon N, Walensky LD. Leshchiner ES, et al. Proc Natl Acad Sci U S A. 2015 Feb 10;112(6):1761-6. doi: 10.1073/pnas.1413185112. Epub 2015 Jan 26. Proc Natl Acad Sci U S A. 2015. PMID: 25624485 Free PMC article.

4

Multimodal interaction with BCL-2 family proteins underlies the proapoptotic activity of PUMA BH3.

Edwards AL, Gavathiotis E, LaBelle JL, Braun CR, Opoku-Nsiah KA, Bird GH, Walensky LD. Edwards AL, et al. Chem Biol. 2013 Jul 25;20(7):888-902. doi: 10.1016/j.chembiol.2013.06.007. Chem Biol. 2013. PMID: 23890007 Free PMC article.

5

Mucosal delivery of a double-stapled RSV peptide prevents nasopulmonary infection.

Bird GH, Boyapalle S, Wong T, Opoku-Nsiah K, Bedi R, Crannell WC, Perry AF, Nguyen H, Sampayo V, Devareddy A, Mohapatra S, Mohapatra SS, Walensky LD. Bird GH, et al. J Clin Invest. 2014 May;124(5):2113-24. doi: 10.1172/JCI71856. Epub 2014 Apr 17. J Clin Invest. 2014. PMID: 24743147 Free PMC article.

6

Specificity for latent C termini links the E3 ubiquitin ligase CHIP to caspases.

Ravalin M, Theofilas P, Basu K, Opoku-Nsiah KA, Assimon VA, Medina-Cleghorn D, Chen YF, Bohn MF, Arkin M, Grinberg LT, Craik CS, Gestwicki JE. Ravalin M, et al. Among authors: opoku nsiah ka. Nat Chem Biol. 2019 Aug;15(8):786-794. doi: 10.1038/s41589-019-0322-6. Epub 2019 Jul 18. Nat Chem Biol. 2019. PMID: 31320752 Free PMC article.

7

Deubiquitinase Usp12 functions noncatalytically to induce autophagy and confer neuroprotection in models of Huntington's disease.

Aron R, Pellegrini P, Green EW, Maddison DC, Opoku-Nsiah K, Oliveira AO, Wong JS, Daub AC, Giorgini F, Muchowski P, Finkbeiner S. Aron R, et al. Among authors: opoku nsiah k. Nat Commun. 2018 Sep 28;9(1):3191. doi: 10.1038/s41467-018-05653-z. Nat Commun. 2018. PMID: 30266909 Free PMC article.

8

Aim for the core: suitability of the ubiquitin-independent 20S proteasome as a drug target in neurodegeneration.

Opoku-Nsiah KA, Gestwicki JE. Opoku-Nsiah KA, et al. Transl Res. 2018 Aug;198:48-57. doi: 10.1016/j.trsl.2018.05.002. Epub 2018 Jun 19. Transl Res. 2018. PMID: 30244692 Free PMC article. Review.

9

The YΦ motif defines the structure-activity relationships of human 20S proteasome activators.

Opoku-Nsiah KA, de la Pena AH, Williams SK, Chopra N, Sali A, Lander GC, Gestwicki JE. Opoku-Nsiah KA, et al. Nat Commun. 2022 Mar 9;13(1):1226. doi: 10.1038/s41467-022-28864-x. Nat Commun. 2022. PMID: 35264557 Free PMC article.

10

Author Correction: Deubiquitinase Usp12 functions noncatalytically to induce autophagy and confer neuroprotection in models of Huntington's disease.

Aron R, Pellegrini P, Green EW, Maddison DC, Opoku-Nsiah K, Osório Oliveira A, Wong JS, Daub AC, Giorgini F, Muchowski P, Finkbeiner S. Aron R, et al. Among authors: opoku nsiah k. Nat Commun. 2020 Feb 21;11(1):1065. doi: 10.1038/s41467-020-14582-9. Nat Commun. 2020. PMID: 32081961 Free PMC article.

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