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Biofilm-associated bacterial amyloids dampen inflammation in the gut: oral treatment with curli fibres reduces the severity of hapten-induced colitis in mice.
NPJ Biofilms Microbiomes. 2015;1:15019-. doi: 10.1038/npjbiofilms.2015.19. Epub 2015 Oct 14.
NPJ Biofilms Microbiomes. 2015.
PMID: 26855788
Free PMC article.
Microbial amyloids induce interleukin 17A (IL-17A) and IL-22 responses via Toll-like receptor 2 activation in the intestinal mucosa.
Nishimori JH, Newman TN, Oppong GO, Rapsinski GJ, Yen JH, Biesecker SG, Wilson RP, Butler BP, Winter MG, Tsolis RM, Ganea D, Tükel Ç.
Nishimori JH, et al. Among authors: oppong go.
Infect Immun. 2012 Dec;80(12):4398-408. doi: 10.1128/IAI.00911-12. Epub 2012 Oct 1.
Infect Immun. 2012.
PMID: 23027540
Free PMC article.
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Epithelial cells augment barrier function via activation of the Toll-like receptor 2/phosphatidylinositol 3-kinase pathway upon recognition of Salmonella enterica serovar Typhimurium curli fibrils in the gut.
Oppong GO, Rapsinski GJ, Newman TN, Nishimori JH, Biesecker SG, Tükel Ç.
Oppong GO, et al.
Infect Immun. 2013 Feb;81(2):478-86. doi: 10.1128/IAI.00453-12. Epub 2012 Dec 3.
Infect Immun. 2013.
PMID: 23208603
Free PMC article.
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CD14 protein acts as an adaptor molecule for the immune recognition of Salmonella curli fibers.
Rapsinski GJ, Newman TN, Oppong GO, van Putten JPM, Tükel Ç.
Rapsinski GJ, et al. Among authors: oppong go.
J Biol Chem. 2013 May 17;288(20):14178-14188. doi: 10.1074/jbc.M112.447060. Epub 2013 Apr 2.
J Biol Chem. 2013.
PMID: 23548899
Free PMC article.
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Toll-like receptor 2 and NLRP3 cooperate to recognize a functional bacterial amyloid, curli.
Rapsinski GJ, Wynosky-Dolfi MA, Oppong GO, Tursi SA, Wilson RP, Brodsky IE, Tükel Ç.
Rapsinski GJ, et al. Among authors: oppong go.
Infect Immun. 2015 Feb;83(2):693-701. doi: 10.1128/IAI.02370-14. Epub 2014 Nov 24.
Infect Immun. 2015.
PMID: 25422268
Free PMC article.
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Amyloid-DNA Composites of Bacterial Biofilms Stimulate Autoimmunity.
Gallo PM, Rapsinski GJ, Wilson RP, Oppong GO, Sriram U, Goulian M, Buttaro B, Caricchio R, Gallucci S, Tükel Ç.
Gallo PM, et al. Among authors: oppong go.
Immunity. 2015 Jun 16;42(6):1171-84. doi: 10.1016/j.immuni.2015.06.002.
Immunity. 2015.
PMID: 26084027
Free PMC article.
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