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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2005 1
2006 3
2007 1
2009 4
2010 2
2011 2
2012 8
2013 9
2014 14
2015 13
2016 10
2017 6
2018 14
2019 12
2020 5
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92 results
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Opportunities for genomic clinical decision support interventions.
Overby CL, Kohane I, Kannry JL, Williams MS, Starren J, Bottinger E, Gottesman O, Denny JC, Weng C, Tarczy-Hornoch P, Hripcsak G. Overby CL, et al. Genet Med. 2013 Oct;15(10):817-23. doi: 10.1038/gim.2013.128. Epub 2013 Sep 19. Genet Med. 2013. PMID: 24051479 Free PMC article. No abstract available.
An integrated clinical and genomic information system for cancer precision medicine.
Jang Y, Choi T, Kim J, Park J, Seo J, Kim S, Kwon Y, Lee S, Lee S. Jang Y, et al. BMC Med Genomics. 2018 Apr 20;11(Suppl 2):34. doi: 10.1186/s12920-018-0347-9. BMC Med Genomics. 2018. PMID: 29697362 Free PMC article.
BACKGROUND: Increasing affordability of next-generation sequencing (NGS) has created an opportunity for realizing genomically-informed personalized cancer therapy as a path to precision oncology. ...An elaborate and practical information system is urgently needed to …
BACKGROUND: Increasing affordability of next-generation sequencing (NGS) has created an opportunity for realizing genomically- …
Whither systems medicine?
Apweiler R, Beissbarth T, Berthold MR, Blüthgen N, Burmeister Y, Dammann O, Deutsch A, Feuerhake F, Franke A, Hasenauer J, Hoffmann S, Höfer T, Jansen PL, Kaderali L, Klingmüller U, Koch I, Kohlbacher O, Kuepfer L, Lammert F, Maier D, Pfeifer N, Radde N, Rehm M, Roeder I, Saez-Rodriguez J, Sax U, Schmeck B, Schuppert A, Seilheimer B, Theis FJ, Vera J, Wolkenhauer O. Apweiler R, et al. Exp Mol Med. 2018 Mar 2;50(3):e453. doi: 10.1038/emm.2017.290. Exp Mol Med. 2018. PMID: 29497170 Free PMC article. Review.
Systems medicine is the interdisciplinary approach wherein physicians and clinical investigators team up with experts from biology, biostatistics, informatics, mathematics and computational modeling to develop methods to use new and stored data to the benefit
Systems medicine is the interdisciplinary approach wherein physicians and clinical investigators team up with experts from bio
Opportunities to implement a sustainable genomic medicine program: lessons learned from the IGNITE Network.
Levy KD, Blake K, Fletcher-Hoppe C, Franciosi J, Goto D, Hicks JK, Holmes AM, Kanuri SH, Madden EB, Musty MD, Orlando L, Pratt VM, Ramos M, Wu R, Ginsburg GS. Levy KD, et al. Genet Med. 2019 Mar;21(3):743-747. doi: 10.1038/s41436-018-0080-y. Epub 2018 Jul 12. Genet Med. 2019. PMID: 29997387 Free PMC article.
Here we describe the findings from the National Human Genome Research Institute's (NHGRI) Implementing GeNomics In pracTicE (IGNITE) Network in identifying key constructs, opportunities, and challenges associated with driving sustainability of genom
Here we describe the findings from the National Human Genome Research Institute's (NHGRI) Implementing GeNomics In prac …
Are innovation and new technologies in precision medicine paving a new era in patients centric care?
Seyhan AA, Carini C. Seyhan AA, et al. J Transl Med. 2019 Apr 5;17(1):114. doi: 10.1186/s12967-019-1864-9. J Transl Med. 2019. PMID: 30953518 Free PMC article. Review.
Genetic, genomics, and epigenetic alterations appear to be contributing to different diseases. Deep clinical phenotyping, combined with advanced molecular phenotypic profiling, enables the construction of causal network models in which a genomic region is pro …
Genetic, genomics, and epigenetic alterations appear to be contributing to different diseases. Deep clinical phenotyping, comb …
Genotyping and genomic profiling of non-small-cell lung cancer: implications for current and future therapies.
Li T, Kung HJ, Mack PC, Gandara DR. Li T, et al. J Clin Oncol. 2013 Mar 10;31(8):1039-49. doi: 10.1200/JCO.2012.45.3753. Epub 2013 Feb 11. J Clin Oncol. 2013. PMID: 23401433 Free PMC article. Review.
Recent technology advances in multiplex genotyping and high-throughput genomic profiling by next-generation sequencing technologies now offer the possibility of rapidly and comprehensively interrogating the cancer genome of individual patients from small tumor biops …
Recent technology advances in multiplex genotyping and high-throughput genomic profiling by next-generation sequencing technologies n …
Analyzing the clinical actionability of germline pharmacogenomic findings in oncology.
Wellmann R, Borden BA, Danahey K, Nanda R, Polite BN, Stadler WM, Ratain MJ, O'Donnell PH. Wellmann R, et al. Cancer. 2018 Jul 15;124(14):3052-3065. doi: 10.1002/cncr.31382. Epub 2018 May 9. Cancer. 2018. PMID: 29742281 Free PMC article.
The authors hypothesized that a critical number of clinically actionable germline pharmacogenomic associations exist, representing clinical implementation opportunities. ...Associations from studies of high methodologic quality were deemed potentially clinically act …
The authors hypothesized that a critical number of clinically actionable germline pharmacogenomic associations exist, representing clinic
Epigenome-based cancer risk prediction: rationale, opportunities and challenges.
Widschwendter M, Jones A, Evans I, Reisel D, Dillner J, Sundström K, Steyerberg EW, Vergouwe Y, Wegwarth O, Rebitschek FG, Siebert U, Sroczynski G, de Beaufort ID, Bolt I, Cibula D, Zikan M, Bjørge L, Colombo N, Harbeck N, Dudbridge F, Tasse AM, Knoppers BM, Joly Y, Teschendorff AE, Pashayan N; FORECEE (4C) Consortium. Widschwendter M, et al. Nat Rev Clin Oncol. 2018 May;15(5):292-309. doi: 10.1038/nrclinonc.2018.30. Epub 2018 Feb 27. Nat Rev Clin Oncol. 2018. PMID: 29485132 Free article. Review.
In particular, the cell type specificity of DNA methylation and the extensive cellular heterogeneity of the easily accessible surrogate cells that might contain information relevant to less accessible tissues necessitates the use of novel methods in order to account for th …
In particular, the cell type specificity of DNA methylation and the extensive cellular heterogeneity of the easily accessible surrogate cell …
Genome analysis and knowledge-driven variant interpretation with TGex.
Dahary D, Golan Y, Mazor Y, Zelig O, Barshir R, Twik M, Iny Stein T, Rosner G, Kariv R, Chen F, Zhang Q, Shen Y, Safran M, Lancet D, Fishilevich S. Dahary D, et al. BMC Med Genomics. 2019 Dec 30;12(1):200. doi: 10.1186/s12920-019-0647-8. BMC Med Genomics. 2019. PMID: 31888639 Free PMC article.
BACKGROUND: The clinical genetics revolution ushers in great opportunities, accompanied by significant challenges. The fundamental mission in clinical genetics is to analyze genomes, and to identify the most relevant genetic variations underlying a pat …
BACKGROUND: The clinical genetics revolution ushers in great opportunities, accompanied by significant challenges. The fundame …
Information technology and precision medicine.
Carney PH. Carney PH. Semin Oncol Nurs. 2014 May;30(2):124-9. doi: 10.1016/j.soncn.2014.03.006. Semin Oncol Nurs. 2014. PMID: 24794086 Review.
OBJECTIVES: To provide oncology nurses with an overview of clinical decision support (CDS) and explore opportunities for genomic CDS interventions. The nation's first personalized cancer decision support tool, My Canc …
OBJECTIVES: To provide oncology nurses with an overview of clinical decision support (CDS) and explore opportunities
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