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Oral Paracetamol Versus Combination Oral Analgesics for Acute Musculoskeletal Injuries.
Gong J, Colligan M, Kirkpatrick C, Jones P. Gong J, et al. Ann Emerg Med. 2019 Oct;74(4):521-529. doi: 10.1016/j.annemergmed.2019.05.030. Epub 2019 Aug 2. Ann Emerg Med. 2019. PMID: 31378383 Clinical Trial.
STUDY OBJECTIVE: We compare paracetamol with a combination of paracetamol, ibuprofen, and codeine for pain relief in acute minor musculoskeletal injuries. ...No adverse events were serious. CONCLUSION: Combining oral paracetamol …
STUDY OBJECTIVE: We compare paracetamol with a combination of paracetamol, ibuprofen, and codeine for pain relief in …
Systematic review and meta-analysis of oral paracetamol versus combination oral analgesics for acute musculoskeletal injuries.
Scott G, Gong J, Kirkpatrick C, Jones P. Scott G, et al. Emerg Med Australas. 2021 Feb;33(1):107-113. doi: 10.1111/1742-6723.13596. Epub 2020 Aug 31. Emerg Med Australas. 2021. PMID: 32864884
Randomised controlled trials comparing paracetamol with paracetamol plus other oral analgesics in managing acute musculoskeletal injuries (e.g. sprains, contusions) were identified. ...CONCLUSION: Paracetamol monotherapy is a reaso …
Randomised controlled trials comparing paracetamol with paracetamol plus other oral analgesics in managing ac …
Tramadol versus hydrocodone-acetaminophen in acute musculoskeletal pain: a randomized, double-blind clinical trial.
Turturro MA, Paris PM, Larkin GL. Turturro MA, et al. Ann Emerg Med. 1998 Aug;32(2):139-43. doi: 10.1016/s0196-0644(98)70127-1. Ann Emerg Med. 1998. PMID: 9701294 Clinical Trial.
STUDY OBJECTIVE: To evaluate the efficacy of an oral tramadol preparation versus that of an oral hydrocodone-acetaminophen preparation in acute musculoskeletal pain. ...CONCLUSION: Tramadol provides inferior analgesia to hydrocodone-ac …
STUDY OBJECTIVE: To evaluate the efficacy of an oral tramadol preparation versus that of an oral hydrocodone-acetami …
Ketorolac versus acetaminophen-codeine in the emergency department treatment of acute low back pain.
Innes GD, Croskerry P, Worthington J, Beveridge R, Jones D. Innes GD, et al. J Emerg Med. 1998 Jul-Aug;16(4):549-56. doi: 10.1016/s0736-4679(98)00044-4. J Emerg Med. 1998. PMID: 9696169 Clinical Trial.
Given the importance of inflammatory mediators in pain generation and the adverse effects associated with opioids, it is logical to expect that a non-opioid agent with antiinflammatory and analgesic properties would provide excellent analgesia with fewer adverse effects. T …
Given the importance of inflammatory mediators in pain generation and the adverse effects associated with opioids, it is logical to expect t …