Orfi L - Search Results

1

Characterization of a conserved structural determinant controlling protein kinase sensitivity to selective inhibitors.

Blencke S, Zech B, Engkvist O, Greff Z, Orfi L, Horváth Z, Kéri G, Ullrich A, Daub H. Blencke S, et al. Among authors: orfi l. Chem Biol. 2004 May;11(5):691-701. doi: 10.1016/j.chembiol.2004.02.029. Chem Biol. 2004. PMID: 15157880

2

Proteomic characterization of the angiogenesis inhibitor SU6668 reveals multiple impacts on cellular kinase signaling.

Godl K, Gruss OJ, Eickhoff J, Wissing J, Blencke S, Weber M, Degen H, Brehmer D, Orfi L, Horváth Z, Kéri G, Müller S, Cotten M, Ullrich A, Daub H. Godl K, et al. Among authors: orfi l. Cancer Res. 2005 Aug 1;65(15):6919-26. doi: 10.1158/0008-5472.CAN-05-0574. Cancer Res. 2005. PMID: 16061676 Free article.

3

AXL is a potential target for therapeutic intervention in breast cancer progression.

Zhang YX, Knyazev PG, Cheburkin YV, Sharma K, Knyazev YP, Orfi L, Szabadkai I, Daub H, Kéri G, Ullrich A. Zhang YX, et al. Among authors: orfi l. Cancer Res. 2008 Mar 15;68(6):1905-15. doi: 10.1158/0008-5472.CAN-07-2661. Cancer Res. 2008. PMID: 18339872

4

Combined inhibition of AXL, Lyn and p130Cas kinases block migration of triple negative breast cancer cells.

Pénzes K, Baumann C, Szabadkai I, Orfi L, Kéri G, Ullrich A, Torka R. Pénzes K, et al. Among authors: orfi l. Cancer Biol Ther. 2014;15(11):1571-82. doi: 10.4161/15384047.2014.956634. Cancer Biol Ther. 2014. PMID: 25482942 Free PMC article.

5

Discovery and Biological Evaluation of Novel Dual EGFR/c-Met Inhibitors.

Szokol B, Gyulavári P, Kurkó I, Baska F, Szántai-Kis C, Greff Z, Orfi Z, Peták I, Pénzes K, Torka R, Ullrich A, Orfi L, Vántus T, Kéri G. Szokol B, et al. Among authors: orfi z, orfi l. ACS Med Chem Lett. 2014 Jan 30;5(4):298-303. doi: 10.1021/ml4003309. eCollection 2014 Apr 10. ACS Med Chem Lett. 2014. PMID: 24900830 Free PMC article.

6

Activation of HER3 interferes with antitumor effects of Axl receptor tyrosine kinase inhibitors: suggestion of combination therapy.

Torka R, Pénzes K, Gusenbauer S, Baumann C, Szabadkai I, Őrfi L, Kéri G, Ullrich A. Torka R, et al. Among authors: orfi l. Neoplasia. 2014 Apr;16(4):301-18. doi: 10.1016/j.neo.2014.03.009. Neoplasia. 2014. PMID: 24862757 Free PMC article.

7

Discovery of N-[4-(Quinolin-4-yloxy)phenyl]benzenesulfonamides as Novel AXL Kinase Inhibitors.

Szabadkai I, Torka R, Garamvölgyi R, Baska F, Gyulavári P, Boros S, Illyés E, Choidas A, Ullrich A, Őrfi L. Szabadkai I, et al. Among authors: orfi l. J Med Chem. 2018 Jul 26;61(14):6277-6292. doi: 10.1021/acs.jmedchem.8b00672. Epub 2018 Jul 9. J Med Chem. 2018. PMID: 29928803

8

Determination of human serum alpha1-acid glycoprotein and albumin binding of various marketed and preclinical kinase inhibitors.

Zsila F, Fitos I, Bencze G, Kéri G, Orfi L. Zsila F, et al. Among authors: orfi l. Curr Med Chem. 2009;16(16):1964-77. doi: 10.2174/092986709788682191. Curr Med Chem. 2009. PMID: 19519376 Review.

9

Identification of protein kinase inhibitors with a selective negative effect on the viability of Epstein-Barr virus infected B cell lines.

Mavromatidis V, Varga Z, Waczek F, Őrfi Z, Őrfi L, Kéri G, Mosialos G. Mavromatidis V, et al. Among authors: orfi z, orfi l. PLoS One. 2014 Apr 23;9(4):e95688. doi: 10.1371/journal.pone.0095688. eCollection 2014. PLoS One. 2014. PMID: 24759913 Free PMC article.

10

Novel compounds reducing IRS-1 serine phosphorylation for treatment of diabetes.

Simon-Szabó L, Kokas M, Greff Z, Boros S, Bánhegyi P, Zsákai L, Szántai-Kis C, Vantus T, Mandl J, Bánhegyi G, Vályi-Nagy I, Őrfi L, Ullrich A, Csala M, Kéri G. Simon-Szabó L, et al. Among authors: orfi l. Bioorg Med Chem Lett. 2016 Jan 15;26(2):424-428. doi: 10.1016/j.bmcl.2015.11.099. Epub 2015 Nov 28. Bioorg Med Chem Lett. 2016. PMID: 26704265

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