Orho-Melander M - Search Results

1

Role of TCF7L2 risk variant and dietary fibre intake on incident type 2 diabetes.

Hindy G, Sonestedt E, Ericson U, Jing XJ, Zhou Y, Hansson O, Renström E, Wirfält E, Orho-Melander M. Hindy G, et al. Diabetologia. 2012 Oct;55(10):2646-2654. doi: 10.1007/s00125-012-2634-x. Epub 2012 Jul 11. Diabetologia. 2012. PMID: 22782288 Free PMC article.

2

A paired-sibling analysis of the XbaI polymorphism in the muscle glycogen synthase gene.

Orho-Melander M, Almgren P, Kanninen T, Forsblom C, Groop LC. Orho-Melander M, et al. Diabetologia. 1999 Sep;42(9):1138-45. doi: 10.1007/s001250051282. Diabetologia. 1999. PMID: 10447527

3

Interaction between the Asn291Ser variant of the LPL gene and insulin resistance on dyslipidaemia in high risk individuals for Type 2 diabetes mellitus.

Klannemark M, Suurinkeroinen L, Orho-Melander M, Groop L, Taskinen MR. Klannemark M, et al. Diabet Med. 2000 Aug;17(8):599-605. doi: 10.1046/j.1464-5491.2000.00343.x. Diabet Med. 2000. PMID: 11073182

4

Common variants in the beta2-(Gln27Glu) and beta3-(Trp64Arg)--adrenoceptor genes are associated with elevated serum NEFA concentrations and type II diabetes.

Carlsson M, Orho-Melander M, Hedenbro J, Groop LC. Carlsson M, et al. Diabetologia. 2001 May;44(5):629-36. doi: 10.1007/s001250051670. Diabetologia. 2001. PMID: 11380082

5

Characterization of a naturally occurring mutation (L107I) in the HNF1 alpha (MODY3) gene.

Cervin C, Orho-Melander M, Ridderstråle M, Lehto M, Barg S, Groop L, Cilio CM. Cervin C, et al. Diabetologia. 2002 Dec;45(12):1703-8. doi: 10.1007/s00125-002-0977-4. Epub 2002 Oct 19. Diabetologia. 2002. PMID: 12488960

6

Parallel manifestation of insulin resistance and beta cell decompensation is compatible with a common defect in Type 2 diabetes.

Tripathy D, Eriksson KF, Orho-Melander M, Fredriksson J, Ahlqvist G, Groop L. Tripathy D, et al. Diabetologia. 2004 May;47(5):782-93. doi: 10.1007/s00125-004-1393-8. Epub 2004 Apr 28. Diabetologia. 2004. PMID: 15114470

7

Genetic prediction of future type 2 diabetes.

Lyssenko V, Almgren P, Anevski D, Orho-Melander M, Sjögren M, Saloranta C, Tuomi T, Groop L; Botnia Study Group. Lyssenko V, et al. PLoS Med. 2005 Nov 1;2(12):e345. doi: 10.1371/journal.pmed.0020345. PLoS Med. 2005. PMID: 17570749 Free PMC article. Clinical Trial.

8

Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes.

Lyssenko V, Lupi R, Marchetti P, Del Guerra S, Orho-Melander M, Almgren P, Sjögren M, Ling C, Eriksson KF, Lethagen AL, Mancarella R, Berglund G, Tuomi T, Nilsson P, Del Prato S, Groop L. Lyssenko V, et al. J Clin Invest. 2007 Aug;117(8):2155-63. doi: 10.1172/JCI30706. J Clin Invest. 2007. PMID: 17671651 Free PMC article. Clinical Trial.

9

The search for putative unifying genetic factors for components of the metabolic syndrome.

Sjögren M, Lyssenko V, Jonsson A, Berglund G, Nilsson P, Groop L, Orho-Melander M. Sjögren M, et al. Diabetologia. 2008 Dec;51(12):2242-51. doi: 10.1007/s00125-008-1151-4. Epub 2008 Oct 14. Diabetologia. 2008. PMID: 18853134

10

A common variant in PNPLA3, which encodes adiponutrin, is associated with liver fat content in humans.

Kotronen A, Johansson LE, Johansson LM, Roos C, Westerbacka J, Hamsten A, Bergholm R, Arkkila P, Arola J, Kiviluoto T, Fisher RM, Ehrenborg E, Orho-Melander M, Ridderstråle M, Groop L, Yki-Järvinen H. Kotronen A, et al. Diabetologia. 2009 Jun;52(6):1056-60. doi: 10.1007/s00125-009-1285-z. Epub 2009 Feb 18. Diabetologia. 2009. PMID: 19224197 Free article.

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