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Virological outcomes of boosted protease inhibitor-based first-line ART in subjects harbouring thymidine analogue-associated mutations as the sole form of transmitted drug resistance.
Geretti AM, White E, Orkin C, Tostevin A, Tilston P, Chadwick D, Leen C, Sabin C, Dunn DT; UK HIV Drug Resistance Database and UK CHIC Study. Geretti AM, et al. Among authors: orkin c. J Antimicrob Chemother. 2019 Mar 1;74(3):746-753. doi: 10.1093/jac/dky468. J Antimicrob Chemother. 2019. PMID: 30544247 Free PMC article.
Increased duration of viral suppression is associated with lower viral rebound rates in patients with previous treatment failures.
Benzie AA, Bansi LK, Sabin CA, Portsmouth S, Hill T, Johnson M, Gilson R, Easterbrook P, Gazzard B, Fisher M, Orkin C, Dunn D, Delpech V, Taylor GP, Walsh JC, Phillips AN; United Kingdom Collaborative HIV Cohort (CHIC) Study Group. Benzie AA, et al. Among authors: orkin c. AIDS. 2007 Jul 11;21(11):1423-30. doi: 10.1097/QAD.0b013e3281532ca7. AIDS. 2007. PMID: 17589188
Rate of AIDS diseases or death in HIV-infected antiretroviral therapy-naive individuals with high CD4 cell count.
Phillips AN, Gazzard B, Gilson R, Easterbrook P, Johnson M, Walsh J, Leen C, Fisher M, Orkin C, Anderson J, Pillay D, Delpech V, Sabin C, Schwenk A, Dunn D, Gompels M, Hill T, Porter K, Babiker A; UK Collaborative HIV Cohort Study. Phillips AN, et al. Among authors: orkin c. AIDS. 2007 Aug 20;21(13):1717-21. doi: 10.1097/QAD.0b013e32827038bf. AIDS. 2007. PMID: 17690569
Changes in outcome of persons initiating highly active antiretroviral therapy at a CD4 count less than 50 Cells/mm3.
Porter K, Walker S, Hill T, Anderson J, Leen C, Johnson M, Gazzard B, Walsh J, Fisher M, Orkin C, Schwenk A, Gilson R, Easterbrook P, Delpech V, Sabin CA; UK CHIC Study Group. Porter K, et al. Among authors: orkin c. J Acquir Immune Defic Syndr. 2008 Feb 1;47(2):202-5. doi: 10.1097/QAI.0b013e31815b1291. J Acquir Immune Defic Syndr. 2008. PMID: 17971709
Risk of extensive virological failure to the three original antiretroviral drug classes over long-term follow-up from the start of therapy in patients with HIV infection: an observational cohort study.
Phillips AN, Leen C, Wilson A, Anderson J, Dunn D, Schwenk A, Orkin C, Hill T, Fisher M, Walsh J, Pillay D, Bansi L, Gazzard B, Easterbrook P, Gilson R, Johnson M, Sabin CA; UK Collaborative HIV Cohort (CHIC) Study. Phillips AN, et al. Among authors: orkin c. Lancet. 2007 Dec 8;370(9603):1923-8. doi: 10.1016/S0140-6736(07)61815-7. Lancet. 2007. PMID: 18068516
Are previous treatment interruptions associated with higher viral rebound rates in patients with viral suppression?
Bansi LK, Benzie AA, Phillips AN, Portsmouth S, Hill T, Leen C, Schwenk A, Johnson M, Anderson J, Gilson R, Easterbrook P, Gazzard B, Fisher M, Orkin C, Porter K, Pillay D, Taylor GP, Walsh JC, Sabin CA; UK Collaborative HIV Cohort (UK CHIC) Study. Bansi LK, et al. Among authors: orkin c. AIDS. 2008 Jan 30;22(3):349-56. doi: 10.1097/QAD.0b013e3282f4709a. AIDS. 2008. PMID: 18195561
HIV-1 drug resistance in HIV-1-infected children in the United Kingdom from 1998 to 2004.
Chakraborty R, Smith CJ, Dunn D, Green H, Duong T, Doerholt K, Riordon A, Lyall H, Tookey P, Butler K, Sabin CA, Gibb D, Pillay D; Collaborative HIV Paediatric Study; UK Collaborative Group on HIV Drug Resistance. Chakraborty R, et al. Pediatr Infect Dis J. 2008 May;27(5):457-9. doi: 10.1097/INF.0b013e3181646d6f. Pediatr Infect Dis J. 2008. PMID: 18382385
342 results