Orlicky D - Search Results

1

Dietary Lipids Differentially Shape Nonalcoholic Steatohepatitis Progression and the Transcriptome of Kupffer Cells and Infiltrating Macrophages.

McGettigan B, McMahan R, Orlicky D, Burchill M, Danhorn T, Francis P, Cheng LL, Golden-Mason L, Jakubzick CV, Rosen HR. McGettigan B, et al. Among authors: orlicky d. Hepatology. 2019 Jul;70(1):67-83. doi: 10.1002/hep.30401. Epub 2019 Feb 27. Hepatology. 2019. PMID: 30516830 Free PMC article.

2

Increased susceptibility of natural killer T-cell-deficient mice to acetaminophen-induced liver injury.

Martin-Murphy BV, Kominsky DJ, Orlicky DJ, Donohue TM Jr, Ju C. Martin-Murphy BV, et al. Hepatology. 2013 Apr;57(4):1575-84. doi: 10.1002/hep.26134. Epub 2013 Jan 18. Hepatology. 2013. PMID: 23150232 Free PMC article.

3

High-fat and high-sucrose (western) diet induces steatohepatitis that is dependent on fructokinase.

Ishimoto T, Lanaspa MA, Rivard CJ, Roncal-Jimenez CA, Orlicky DJ, Cicerchi C, McMahan RH, Abdelmalek MF, Rosen HR, Jackman MR, MacLean PS, Diggle CP, Asipu A, Inaba S, Kosugi T, Sato W, Maruyama S, Sánchez-Lozada LG, Sautin YY, Hill JO, Bonthron DT, Johnson RJ. Ishimoto T, et al. Hepatology. 2013 Nov;58(5):1632-43. doi: 10.1002/hep.26594. Epub 2013 Oct 8. Hepatology. 2013. PMID: 23813872 Free PMC article.

4

Sevelamer Improves Steatohepatitis, Inhibits Liver and Intestinal Farnesoid X Receptor (FXR), and Reverses Innate Immune Dysregulation in a Mouse Model of Non-alcoholic Fatty Liver Disease.

McGettigan BM, McMahan RH, Luo Y, Wang XX, Orlicky DJ, Porsche C, Levi M, Rosen HR. McGettigan BM, et al. J Biol Chem. 2016 Oct 28;291(44):23058-23067. doi: 10.1074/jbc.M116.731042. Epub 2016 Sep 7. J Biol Chem. 2016. PMID: 27605663 Free PMC article.

5

Cytokine-Producing B Cells Promote Immune-Mediated Bile Duct Injury in Murine Biliary Atresia.

Bednarek J, Traxinger B, Brigham D, Roach J, Orlicky D, Wang D, Pelanda R, Mack CL. Bednarek J, et al. Among authors: orlicky d. Hepatology. 2018 Nov;68(5):1890-1904. doi: 10.1002/hep.30051. Epub 2018 Jul 10. Hepatology. 2018. PMID: 29679373 Free PMC article.

6

Perilipin-2 promotes obesity and progressive fatty liver disease in mice through mechanistically distinct hepatocyte and extra-hepatocyte actions.

Orlicky DJ, Libby AE, Bales ES, McMahan RH, Monks J, La Rosa FG, McManaman JL. Orlicky DJ, et al. J Physiol. 2019 Mar;597(6):1565-1584. doi: 10.1113/JP277140. Epub 2019 Jan 2. J Physiol. 2019. PMID: 30536914 Free PMC article.

7

Oxidized Low-Density Lipoprotein Drives Dysfunction of the Liver Lymphatic System.

Burchill MA, Finlon JM, Goldberg AR, Gillen AE, Dahms PA, McMahan RH, Tye A, Winter AB, Reisz JA, Bohrnsen E, Schafer JB, D'Alessandro A, Orlicky DJ, Kriss MS, Rosen HR, McCullough RL, Jirón Tamburini BA. Burchill MA, et al. Among authors: d alessandro a, orlicky dj. Cell Mol Gastroenterol Hepatol. 2021;11(2):573-595. doi: 10.1016/j.jcmgh.2020.09.007. Epub 2020 Sep 19. Cell Mol Gastroenterol Hepatol. 2021. PMID: 32961356 Free PMC article.

8

JAK1 Inhibition Blocks Lethal Immune Hypersensitivity in a Mouse Model of Down Syndrome.

Tuttle KD, Waugh KA, Araya P, Minter R, Orlicky DJ, Ludwig M, Andrysik Z, Burchill MA, Tamburini BAJ, Sempeck C, Smith K, Granrath R, Tracy D, Baxter J, Espinosa JM, Sullivan KD. Tuttle KD, et al. Among authors: orlicky dj. Cell Rep. 2020 Nov 17;33(7):108407. doi: 10.1016/j.celrep.2020.108407. Cell Rep. 2020. PMID: 33207208 Free PMC article.

9

NF-κB Regulation of LRH-1 and ABCG5/8 Potentiates Phytosterol Role in the Pathogenesis of Parenteral Nutrition-Associated Cholestasis.

Ghosh S, Devereaux MW, Anderson AL, Gehrke S, Reisz JA, D'Alessandro A, Orlicky DJ, Lovell M, El Kasmi KC, Shearn CT, Sokol RJ. Ghosh S, et al. Among authors: d alessandro a, orlicky dj. Hepatology. 2021 Dec;74(6):3284-3300. doi: 10.1002/hep.32071. Epub 2021 Aug 27. Hepatology. 2021. PMID: 34310734 Free PMC article.

10

Pharmacologic activation of hepatic farnesoid X receptor prevents parenteral nutrition-associated cholestasis in mice.

El Kasmi KC, Ghosh S, Anderson AL, Devereaux MW, Balasubramaniyan N, D'Alessandro A, Orlicky DJ, Suchy FJ, Shearn CT, Sokol RJ. El Kasmi KC, et al. Among authors: d alessandro a, orlicky dj. Hepatology. 2022 Feb;75(2):252-265. doi: 10.1002/hep.32101. Epub 2021 Dec 7. Hepatology. 2022. PMID: 34387888

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