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Putative cis-regulatory drivers in colorectal cancer.
Ongen H, Andersen CL, Bramsen JB, Oster B, Rasmussen MH, Ferreira PG, Sandoval J, Vidal E, Whiffin N, Planchon A, Padioleau I, Bielser D, Romano L, Tomlinson I, Houlston RS, Esteller M, Orntoft TF, Dermitzakis ET. Ongen H, et al. Among authors: orntoft tf. Nature. 2014 Aug 7;512(7512):87-90. doi: 10.1038/nature13602. Epub 2014 Jul 23. Nature. 2014. PMID: 25079323
A DERL3-associated defect in the degradation of SLC2A1 mediates the Warburg effect.
Lopez-Serra P, Marcilla M, Villanueva A, Ramos-Fernandez A, Palau A, Leal L, Wahi JE, Setien-Baranda F, Szczesna K, Moutinho C, Martinez-Cardus A, Heyn H, Sandoval J, Puertas S, Vidal A, Sanjuan X, Martinez-Balibrea E, Viñals F, Perales JC, Bramsem JB, Ørntoft TF, Andersen CL, Tabernero J, McDermott U, Boxer MB, Vander Heiden MG, Albar JP, Esteller M. Lopez-Serra P, et al. Among authors: orntoft tf. Nat Commun. 2014 Apr 3;5:3608. doi: 10.1038/ncomms4608. Nat Commun. 2014. PMID: 24699711 Free PMC article.
Distinct expression profile in fumarate-hydratase-deficient uterine fibroids.
Vanharanta S, Pollard PJ, Lehtonen HJ, Laiho P, Sjöberg J, Leminen A, Aittomäki K, Arola J, Kruhoffer M, Orntoft TF, Tomlinson IP, Kiuru M, Arango D, Aaltonen LA. Vanharanta S, et al. Among authors: orntoft tf. Hum Mol Genet. 2006 Jan 1;15(1):97-103. doi: 10.1093/hmg/ddi431. Epub 2005 Nov 30. Hum Mol Genet. 2006. PMID: 16319128
DNA copy-number alterations underlie gene expression differences between microsatellite stable and unstable colorectal cancers.
Jorissen RN, Lipton L, Gibbs P, Chapman M, Desai J, Jones IT, Yeatman TJ, East P, Tomlinson IP, Verspaget HW, Aaltonen LA, Kruhøffer M, Orntoft TF, Andersen CL, Sieber OM. Jorissen RN, et al. Among authors: orntoft tf. Clin Cancer Res. 2008 Dec 15;14(24):8061-9. doi: 10.1158/1078-0432.CCR-08-1431. Clin Cancer Res. 2008. PMID: 19088021 Free PMC article.
Unregulated smooth-muscle myosin in human intestinal neoplasia.
Alhopuro P, Phichith D, Tuupanen S, Sammalkorpi H, Nybondas M, Saharinen J, Robinson JP, Yang Z, Chen LQ, Orntoft T, Mecklin JP, Järvinen H, Eng C, Moeslein G, Shibata D, Houlston RS, Lucassen A, Tomlinson IP, Launonen V, Ristimäki A, Arango D, Karhu A, Sweeney HL, Aaltonen LA. Alhopuro P, et al. Proc Natl Acad Sci U S A. 2008 Apr 8;105(14):5513-8. doi: 10.1073/pnas.0801213105. Epub 2008 Apr 7. Proc Natl Acad Sci U S A. 2008. PMID: 18391202 Free PMC article.
Mutations in the circadian gene CLOCK in colorectal cancer.
Alhopuro P, Björklund M, Sammalkorpi H, Turunen M, Tuupanen S, Biström M, Niittymäki I, Lehtonen HJ, Kivioja T, Launonen V, Saharinen J, Nousiainen K, Hautaniemi S, Nuorva K, Mecklin JP, Järvinen H, Orntoft T, Arango D, Lehtonen R, Karhu A, Taipale J, Aaltonen LA. Alhopuro P, et al. Mol Cancer Res. 2010 Jul;8(7):952-60. doi: 10.1158/1541-7786.MCR-10-0086. Epub 2010 Jun 15. Mol Cancer Res. 2010. PMID: 20551151
Germline fumarate hydratase mutations in patients with ovarian mucinous cystadenoma.
Ylisaukko-oja SK, Cybulski C, Lehtonen R, Kiuru M, Matyjasik J, Szymañska A, Szymañska-Pasternak J, Dyrskjot L, Butzow R, Orntoft TF, Launonen V, Lubiñski J, Aaltonen LA. Ylisaukko-oja SK, et al. Among authors: orntoft tf. Eur J Hum Genet. 2006 Jul;14(7):880-3. doi: 10.1038/sj.ejhg.5201630. Epub 2006 Apr 26. Eur J Hum Genet. 2006. PMID: 16639410
Metastasis-Associated Gene Expression Changes Predict Poor Outcomes in Patients with Dukes Stage B and C Colorectal Cancer.
Jorissen RN, Gibbs P, Christie M, Prakash S, Lipton L, Desai J, Kerr D, Aaltonen LA, Arango D, Kruhøffer M, Orntoft TF, Andersen CL, Gruidl M, Kamath VP, Eschrich S, Yeatman TJ, Sieber OM. Jorissen RN, et al. Among authors: orntoft tf. Clin Cancer Res. 2009 Dec 15;15(24):7642-7651. doi: 10.1158/1078-0432.CCR-09-1431. Clin Cancer Res. 2009. PMID: 19996206 Free PMC article.
379 results