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MiOS, an integrated imaging and computational strategy to model gene folding with nucleosome resolution.
Neguembor MV, Arcon JP, Buitrago D, Lema R, Walther J, Garate X, Martin L, Romero P, AlHaj Abed J, Gut M, Blanc J, Lakadamyali M, Wu CT, Brun Heath I, Orozco M, Dans PD, Cosma MP. Neguembor MV, et al. Among authors: orozco m. Nat Struct Mol Biol. 2022 Oct;29(10):1011-1023. doi: 10.1038/s41594-022-00839-y. Epub 2022 Oct 11. Nat Struct Mol Biol. 2022. PMID: 36220894 Free PMC article.
Exploring polymorphisms in B-DNA helical conformations.
Dans PD, Pérez A, Faustino I, Lavery R, Orozco M. Dans PD, et al. Among authors: orozco m. Nucleic Acids Res. 2012 Nov;40(21):10668-78. doi: 10.1093/nar/gks884. Epub 2012 Sep 24. Nucleic Acids Res. 2012. PMID: 23012264 Free PMC article.
Epigenomic analysis detects widespread gene-body DNA hypomethylation in chronic lymphocytic leukemia.
Kulis M, Heath S, Bibikova M, Queirós AC, Navarro A, Clot G, Martínez-Trillos A, Castellano G, Brun-Heath I, Pinyol M, Barberán-Soler S, Papasaikas P, Jares P, Beà S, Rico D, Ecker S, Rubio M, Royo R, Ho V, Klotzle B, Hernández L, Conde L, López-Guerra M, Colomer D, Villamor N, Aymerich M, Rozman M, Bayes M, Gut M, Gelpí JL, Orozco M, Fan JB, Quesada V, Puente XS, Pisano DG, Valencia A, López-Guillermo A, Gut I, López-Otín C, Campo E, Martín-Subero JI. Kulis M, et al. Among authors: orozco m. Nat Genet. 2012 Nov;44(11):1236-42. doi: 10.1038/ng.2443. Epub 2012 Oct 14. Nat Genet. 2012. PMID: 23064414
Direct measurement of the dielectric polarization properties of DNA.
Cuervo A, Dans PD, Carrascosa JL, Orozco M, Gomila G, Fumagalli L. Cuervo A, et al. Among authors: orozco m. Proc Natl Acad Sci U S A. 2014 Sep 2;111(35):E3624-30. doi: 10.1073/pnas.1405702111. Epub 2014 Aug 18. Proc Natl Acad Sci U S A. 2014. PMID: 25136104 Free PMC article.
The structural impact of DNA mismatches.
Rossetti G, Dans PD, Gomez-Pinto I, Ivani I, Gonzalez C, Orozco M. Rossetti G, et al. Among authors: orozco m. Nucleic Acids Res. 2015 Apr 30;43(8):4309-21. doi: 10.1093/nar/gkv254. Epub 2015 Mar 27. Nucleic Acids Res. 2015. PMID: 25820425 Free PMC article.
Parmbsc1: a refined force field for DNA simulations.
Ivani I, Dans PD, Noy A, Pérez A, Faustino I, Hospital A, Walther J, Andrio P, Goñi R, Balaceanu A, Portella G, Battistini F, Gelpí JL, González C, Vendruscolo M, Laughton CA, Harris SA, Case DA, Orozco M. Ivani I, et al. Among authors: orozco m. Nat Methods. 2016 Jan;13(1):55-8. doi: 10.1038/nmeth.3658. Epub 2015 Nov 16. Nat Methods. 2016. PMID: 26569599 Free PMC article.
Multiscale simulation of DNA.
Dans PD, Walther J, Gómez H, Orozco M. Dans PD, et al. Among authors: orozco m. Curr Opin Struct Biol. 2016 Apr;37:29-45. doi: 10.1016/j.sbi.2015.11.011. Epub 2015 Dec 19. Curr Opin Struct Biol. 2016. PMID: 26708341 Free article. Review.
Epigenomic analysis detects aberrant super-enhancer DNA methylation in human cancer.
Heyn H, Vidal E, Ferreira HJ, Vizoso M, Sayols S, Gomez A, Moran S, Boque-Sastre R, Guil S, Martinez-Cardus A, Lin CY, Royo R, Sanchez-Mut JV, Martinez R, Gut M, Torrents D, Orozco M, Gut I, Young RA, Esteller M. Heyn H, et al. Among authors: orozco m. Genome Biol. 2016 Jan 26;17:11. doi: 10.1186/s13059-016-0879-2. Genome Biol. 2016. PMID: 26813288 Free PMC article.
533 results