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GTI-2040. Lorus Therapeutics.
Orr RM. Orr RM. Curr Opin Investig Drugs. 2001 Oct;2(10):1462-6. Curr Opin Investig Drugs. 2001. PMID: 11890366
Clinical studies of antisense oligonucleotides for cancer therapy.
Orr RM, Dorr FA. Orr RM, et al. Methods Mol Med. 2005;106:85-111. doi: 10.1385/1-59259-854-4:085. Methods Mol Med. 2005. PMID: 15375314 Review. No abstract available.
Disruption of WT1 gene expression and exon 5 splicing following cytotoxic drug treatment: antisense down-regulation of exon 5 alters target gene expression and inhibits cell survival.
Renshaw J, Orr RM, Walton MI, Te Poele R, Williams RD, Wancewicz EV, Monia BP, Workman P, Pritchard-Jones K. Renshaw J, et al. Among authors: orr rm. Mol Cancer Ther. 2004 Nov;3(11):1467-84. Mol Cancer Ther. 2004. PMID: 15542786
The cytotoxic action of four ammine/amine platinum(IV) dicarboxylates: a flow cytometric study.
Ormerod MG, Orr RM, O'Neill CF, Chwalinski T, Titley JC, Kelland LR, Harrap KR. Ormerod MG, et al. Among authors: orr rm. Br J Cancer. 1996 Dec;74(12):1935-43. doi: 10.1038/bjc.1996.656. Br J Cancer. 1996. PMID: 8980393 Free PMC article.
Novel trans platinum complexes: comparative in vitro and in vivo activity against platinum-sensitive and resistant murine tumours.
Goddard PM, Orr RM, Valenti MR, Barnard CF, Murrer BA, Kelland LR, Harrap KR. Goddard PM, et al. Among authors: orr rm. Anticancer Res. 1996 Jan-Feb;16(1):33-8. Anticancer Res. 1996. PMID: 8615631
Synthesis and ribonucleotide reductase inhibitory activity of analogues of 2,3-dihydro-1H-imidazo[1,2-b]pyrazole (IMPY).
Goddard AJ, Orr RM, Stock JA, Wilman DE. Goddard AJ, et al. Among authors: orr rm. Anticancer Drug Des. 1987 Dec;2(3):235-45. Anticancer Drug Des. 1987. PMID: 3329526
Platinum coordination complexes which circumvent cisplatin resistance.
Harrap KR, Kelland LR, Jones M, Goddard PM, Orr RM, Morgan SE, Murrer BA, Abrams MJ, Giandomenico CM, Cobbleigh T. Harrap KR, et al. Among authors: orr rm. Adv Enzyme Regul. 1991;31:31-43. doi: 10.1016/0065-2571(91)90007-9. Adv Enzyme Regul. 1991. PMID: 1877393
Technology evaluation: leukemia therapy, University of Pennsylvania.
Orr RM. Orr RM. Curr Opin Mol Ther. 1999 Jun;1(3):399-403. Curr Opin Mol Ther. 1999. PMID: 11713805
Technology evaluation: fomivirsen, Isis Pharmaceuticals Inc/CIBA vision.
Orr RM. Orr RM. Curr Opin Mol Ther. 2001 Jun;3(3):288-94. Curr Opin Mol Ther. 2001. PMID: 11497353 Review.
Technology evaluation: electroporation therapy, Genetronics Inc.
Orr RM. Orr RM. Curr Opin Mol Ther. 2000 Apr;2(2):205-10. Curr Opin Mol Ther. 2000. PMID: 11249643 Review.
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