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Cyclin D-dependent kinases, INK4 inhibitors and cancer.
Ortega S, Malumbres M, Barbacid M. Ortega S, et al. Biochim Biophys Acta. 2002 Mar 14;1602(1):73-87. doi: 10.1016/s0304-419x(02)00037-9. Biochim Biophys Acta. 2002. PMID: 11960696 Review.
The Ink4/Arf locus is a barrier for iPS cell reprogramming.
Li H, Collado M, Villasante A, Strati K, Ortega S, Cañamero M, Blasco MA, Serrano M. Li H, et al. Among authors: ortega s. Nature. 2009 Aug 27;460(7259):1136-9. doi: 10.1038/nature08290. Epub 2009 Aug 9. Nature. 2009. PMID: 19668188 Free PMC article.
Invasive melanoma in Cdk4-targeted mice.
Sotillo R, García JF, Ortega S, Martin J, Dubus P, Barbacid M, Malumbres M. Sotillo R, et al. Among authors: ortega s. Proc Natl Acad Sci U S A. 2001 Nov 6;98(23):13312-7. doi: 10.1073/pnas.241338598. Epub 2001 Oct 23. Proc Natl Acad Sci U S A. 2001. PMID: 11606789 Free PMC article.
Mice thrive without Cdk4 and Cdk2.
Barrière C, Santamaría D, Cerqueira A, Galán J, Martín A, Ortega S, Malumbres M, Dubus P, Barbacid M. Barrière C, et al. Among authors: ortega s. Mol Oncol. 2007 Jun;1(1):72-83. doi: 10.1016/j.molonc.2007.03.001. Epub 2007 Mar 14. Mol Oncol. 2007. PMID: 19383288 Free PMC article.
283 results