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Selective striatal mtDNA depletion in end-stage Huntington's disease R6/2 mice.
Hering T, Birth N, Taanman JW, Orth M. Hering T, et al. Exp Neurol. 2015 Apr;266:22-9. doi: 10.1016/j.expneurol.2015.02.004. Epub 2015 Feb 12. Exp Neurol. 2015. PMID: 25682918
Mitochondrial cristae remodelling is associated with disrupted OPA1 oligomerisation in the Huntington's disease R6/2 fragment model.
Hering T, Kojer K, Birth N, Hallitsch J, Taanman JW, Orth M. Hering T, et al. Exp Neurol. 2017 Feb;288:167-175. doi: 10.1016/j.expneurol.2016.10.017. Epub 2016 Nov 23. Exp Neurol. 2017. PMID: 27889468
Comparison of Huntington's Disease in Europe and North America.
Orth M, Bronzova J, Tritsch C, Ray Dorsey E, Ferreira JJ, Gemperli A; EHDN REGISTRY and HSG COHORT Investigators. Orth M, et al. Mov Disord Clin Pract. 2016 Oct 24;4(3):358-367. doi: 10.1002/mdc3.12442. eCollection 2017 May-Jun. Mov Disord Clin Pract. 2016. PMID: 30363400 Free PMC article.
β-Defensin Genomic Copy Number Does Not Influence the Age of Onset in Huntington's Disease.
Vittori A, Orth M, Roos RA, Outeiro TF, Giorgini F, Hollox EJ; REGISTRY investigators of the European Huntington’s Disease Network. Vittori A, et al. J Huntingtons Dis. 2013 Mar 27;2(1):107-124. doi: 10.3233/JHD-130047. J Huntingtons Dis. 2013. PMID: 24587836 Free PMC article.
Copy-number variation of the neuronal glucose transporter gene SLC2A3 and age of onset in Huntington's disease.
Vittori A, Breda C, Repici M, Orth M, Roos RA, Outeiro TF, Giorgini F, Hollox EJ; REGISTRY investigators of the European Huntington's Disease Network. Vittori A, et al. Hum Mol Genet. 2014 Jun 15;23(12):3129-37. doi: 10.1093/hmg/ddu022. Epub 2014 Jan 22. Hum Mol Genet. 2014. PMID: 24452335 Free PMC article.
Abnormal peripheral chemokine profile in Huntington's disease.
Wild E, Magnusson A, Lahiri N, Krus U, Orth M, Tabrizi SJ, Björkqvist M. Wild E, et al. PLoS Curr. 2011 Apr 13;3:RRN1231. doi: 10.1371/currents.RRN1231. PLoS Curr. 2011. PMID: 21826115 Free PMC article.
Observing Huntington's Disease: the European Huntington's Disease Network's REGISTRY.
Orth M, Handley OJ, Schwenke C, Dunnett SB, Craufurd D, Ho AK, Wild E, Tabrizi SJ, Landwehrmeyer GB; Investigators of the European Huntington's Disease Network. Orth M, et al. PLoS Curr. 2010 Sep 28;2:RRN1184. doi: 10.1371/currents.RRN1184. PLoS Curr. 2010. PMID: 20890398 Free PMC article.
Natural biological variation of white matter microstructure is accentuated in Huntington's disease.
Gregory S, Crawford H, Seunarine K, Leavitt B, Durr A, Roos RAC, Scahill RI, Tabrizi SJ, Rees G, Langbehn D, Orth M. Gregory S, et al. Hum Brain Mapp. 2018 Sep;39(9):3516-3527. doi: 10.1002/hbm.24191. Epub 2018 Apr 22. Hum Brain Mapp. 2018. PMID: 29682858 Free PMC article.
Identification of symbol digit modality test score extremes in Huntington's disease.
Braisch U, Muche R, Rothenbacher D, Landwehrmeyer GB, Long JD, Orth M; REGISTRY Investigators of the European Huntington's Disease Network and COHORT Investigators of the Huntington Study Group. Braisch U, et al. Am J Med Genet B Neuropsychiatr Genet. 2019 Apr;180(3):232-245. doi: 10.1002/ajmg.b.32719. Epub 2019 Feb 20. Am J Med Genet B Neuropsychiatr Genet. 2019. PMID: 30788902
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