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Activation induced deaminase: how much and where?
Orthwein A, Di Noia JM. Orthwein A, et al. Semin Immunol. 2012 Aug;24(4):246-54. doi: 10.1016/j.smim.2012.05.001. Epub 2012 Jun 9. Semin Immunol. 2012. PMID: 22687198 Review.
53BP1 is a reader of the DNA-damage-induced H2A Lys 15 ubiquitin mark.
Fradet-Turcotte A, Canny MD, Escribano-Díaz C, Orthwein A, Leung CC, Huang H, Landry MC, Kitevski-LeBlanc J, Noordermeer SM, Sicheri F, Durocher D. Fradet-Turcotte A, et al. Among authors: orthwein a. Nature. 2013 Jul 4;499(7456):50-4. doi: 10.1038/nature12318. Epub 2013 Jun 12. Nature. 2013. PMID: 23760478 Free PMC article.
HSP90 inhibitors decrease AID levels and activity in mice and in human cells.
Montamat-Sicotte D, Litzler LC, Abreu C, Safavi S, Zahn A, Orthwein A, Müschen M, Oppezzo P, Muñoz DP, Di Noia JM. Montamat-Sicotte D, et al. Among authors: orthwein a. Eur J Immunol. 2015 Aug;45(8):2365-76. doi: 10.1002/eji.201545462. Epub 2015 May 18. Eur J Immunol. 2015. PMID: 25912253 Free PMC article.
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