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Year Number of Results
2007 1
2009 1
2010 1
2011 1
2012 2
2013 2
2014 1
2015 3
2016 2
2017 5
2018 4
2019 1
2020 2
2021 5
2022 7
2023 3
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42 results

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Page 1
A decade of RAD51C and RAD51D germline variants in cancer.
Boni J, Idani A, Roca C, Feliubadaló L, Tomiak E, Weber E, Foulkes WD, Orthwein A, El Haffaf Z, Lazaro C, Rivera B. Boni J, et al. Among authors: orthwein a. Hum Mutat. 2022 Mar;43(3):285-298. doi: 10.1002/humu.24319. Epub 2021 Dec 30. Hum Mutat. 2022. PMID: 34923718 Review.
Radiation and anti-PD-L1 synergize by stimulating a stem-like T cell population in the tumor-draining lymph node.
Shen Y, Connolly E, Aiello M, Zhou C, Chappa P, Song H, Tippitak P, Clark T, Cardenas M, Prokhnevska N, Mariniello A, Pagadala MS, Dhere VR, Rafiq S, Kesarwala AH, Orthwein A, Thomas SN, Khan MK, Brandon Dixon J, Lesinski GB, Lowe MC, Kissick H, Yu DS, Paulos CM, Schmitt NC, Buchwald ZS. Shen Y, et al. Among authors: orthwein a. Res Sq [Preprint]. 2024 Mar 6:rs.3.rs-3921977. doi: 10.21203/rs.3.rs-3921977/v1. Res Sq. 2024. PMID: 38496632 Free PMC article. Preprint.
FIRRM cooperates with FIGNL1 to promote RAD51 disassembly during DNA repair.
Pinedo-Carpio E, Dessapt J, Beneyton A, Sacre L, Bérubé MA, Villot R, Lavoie EG, Coulombe Y, Blondeau A, Boulais J, Malina A, Luo VM, Lazaratos AM, Côté JF, Mallette FA, Guarné A, Masson JY, Fradet-Turcotte A, Orthwein A. Pinedo-Carpio E, et al. Among authors: orthwein a. Sci Adv. 2023 Aug 9;9(32):eadf4082. doi: 10.1126/sciadv.adf4082. Epub 2023 Aug 9. Sci Adv. 2023. PMID: 37556550 Free PMC article.
A mechanism for the suppression of homologous recombination in G1 cells.
Orthwein A, Noordermeer SM, Wilson MD, Landry S, Enchev RI, Sherker A, Munro M, Pinder J, Salsman J, Dellaire G, Xia B, Peter M, Durocher D. Orthwein A, et al. Nature. 2015 Dec 17;528(7582):422-6. doi: 10.1038/nature16142. Epub 2015 Dec 9. Nature. 2015. PMID: 26649820 Free PMC article.
HELB Is a Feedback Inhibitor of DNA End Resection.
Tkáč J, Xu G, Adhikary H, Young JTF, Gallo D, Escribano-Díaz C, Krietsch J, Orthwein A, Munro M, Sol W, Al-Hakim A, Lin ZY, Jonkers J, Borst P, Brown GW, Gingras AC, Rottenberg S, Masson JY, Durocher D. Tkáč J, et al. Among authors: orthwein a. Mol Cell. 2016 Feb 4;61(3):405-418. doi: 10.1016/j.molcel.2015.12.013. Epub 2016 Jan 7. Mol Cell. 2016. PMID: 26774285 Free article.
POGZ promotes homology-directed DNA repair in an HP1-dependent manner.
Heath J, Cheyou ES, Findlay S, Luo VM, Carpio EP, Lee J, Djerir B, Chen X, Morin T, Lebeau B, Karam M, Bagci H, Grapton D, Ursini-Siegel J, Côté JF, Witcher M, Richard S, Maréchal A, Orthwein A. Heath J, et al. Among authors: orthwein a. EMBO Rep. 2022 Jan 5;23(1):e51041. doi: 10.15252/embr.202051041. Epub 2021 Nov 10. EMBO Rep. 2022. PMID: 34758190 Free PMC article.
Retraction.
Orthwein A, Fradet-Turcotte A, Noordermeer SM, Canny MD, Brun CM, Strecker J, Escribano-Diaz C, Durocher D. Orthwein A, et al. Science. 2025 Jan 10;387(6730):147. doi: 10.1126/science.adv1263. Epub 2025 Jan 9. Science. 2025. PMID: 39787242 No abstract available.
Activation induced deaminase: how much and where?
Orthwein A, Di Noia JM. Orthwein A, et al. Semin Immunol. 2012 Aug;24(4):246-54. doi: 10.1016/j.smim.2012.05.001. Epub 2012 Jun 9. Semin Immunol. 2012. PMID: 22687198 Review.
42 results