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Page 1
Galectin-1 drives pancreatic carcinogenesis through stroma remodeling and Hedgehog signaling activation.
Martínez-Bosch N, Fernández-Barrena MG, Moreno M, Ortiz-Zapater E, Munné-Collado J, Iglesias M, André S, Gabius HJ, Hwang RF, Poirier F, Navas C, Guerra C, Fernández-Zapico ME, Navarro P. Martínez-Bosch N, et al. Cancer Res. 2014 Jul 1;74(13):3512-24. doi: 10.1158/0008-5472.CAN-13-3013. Epub 2014 May 8. Cancer Res. 2014. PMID: 24812270 Free PMC article.
Tissue plasminogen activator induces pancreatic cancer cell proliferation by a non-catalytic mechanism that requires extracellular signal-regulated kinase 1/2 activation through epidermal growth factor receptor and annexin A2.
Ortiz-Zapater E, Peiró S, Roda O, Corominas JM, Aguilar S, Ampurdanés C, Real FX, Navarro P. Ortiz-Zapater E, et al. Am J Pathol. 2007 May;170(5):1573-84. doi: 10.2353/ajpath.2007.060850. Am J Pathol. 2007. PMID: 17456763 Free PMC article.
The ErbB4 CYT2 variant protects EGFR from ligand-induced degradation to enhance cancer cell motility.
Kiuchi T, Ortiz-Zapater E, Monypenny J, Matthews DR, Nguyen LK, Barbeau J, Coban O, Lawler K, Burford B, Rolfe DJ, de Rinaldis E, Dafou D, Simpson MA, Woodman N, Pinder S, Gillett CE, Devauges V, Poland SP, Fruhwirth G, Marra P, Boersma YL, Plückthun A, Gullick WJ, Yarden Y, Santis G, Winn M, Kholodenko BN, Martin-Fernandez ML, Parker P, Tutt A, Ameer-Beg SM, Ng T. Kiuchi T, et al. Sci Signal. 2014 Aug 19;7(339):ra78. doi: 10.1126/scisignal.2005157. Sci Signal. 2014. PMID: 25140053
The architecture of EGFR's basal complexes reveals autoinhibition mechanisms in dimers and oligomers.
Zanetti-Domingues LC, Korovesis D, Needham SR, Tynan CJ, Sagawa S, Roberts SK, Kuzmanic A, Ortiz-Zapater E, Jain P, Roovers RC, Lajevardipour A, van Bergen En Henegouwen PMP, Santis G, Clayton AHA, Clarke DT, Gervasio FL, Shan Y, Shaw DE, Rolfe DJ, Parker PJ, Martin-Fernandez ML. Zanetti-Domingues LC, et al. Nat Commun. 2018 Oct 18;9(1):4325. doi: 10.1038/s41467-018-06632-0. Nat Commun. 2018. PMID: 30337523 Free PMC article.
30 results