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The second-generation active Aβ immunotherapy CAD106 reduces amyloid accumulation in APP transgenic mice while minimizing potential side effects.
Wiessner C, Wiederhold KH, Tissot AC, Frey P, Danner S, Jacobson LH, Jennings GT, Lüönd R, Ortmann R, Reichwald J, Zurini M, Mir A, Bachmann MF, Staufenbiel M. Wiessner C, et al. Among authors: ortmann r. J Neurosci. 2011 Jun 22;31(25):9323-31. doi: 10.1523/JNEUROSCI.0293-11.2011. J Neurosci. 2011. PMID: 21697382 Free PMC article.
Septo-hippocampal system: target for substituted benzamides.
Bischoff S, Bittiger H, Delini-Stula A, Ortmann R. Bischoff S, et al. Among authors: ortmann r. Eur J Pharmacol. 1982 Apr 23;79(3-4):225-32. doi: 10.1016/0014-2999(82)90628-8. Eur J Pharmacol. 1982. PMID: 7201401
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