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Bovine lens acylpeptide hydrolase. Purification and characterization of a tetrameric enzyme resistant to urea denaturation and proteolytic inactivation.
Sharma KK, Ortwerth BJ. Sharma KK, et al. Among authors: ortwerth bj. Eur J Biochem. 1993 Sep 1;216(2):631-7. doi: 10.1111/j.1432-1033.1993.tb18183.x. Eur J Biochem. 1993. PMID: 8375399
Regulation of tissue oxygen levels in the mammalian lens.
McNulty R, Wang H, Mathias RT, Ortwerth BJ, Truscott RJ, Bassnett S. McNulty R, et al. Among authors: ortwerth bj. J Physiol. 2004 Sep 15;559(Pt 3):883-98. doi: 10.1113/jphysiol.2004.068619. Epub 2004 Jul 22. J Physiol. 2004. PMID: 15272034 Free PMC article.
Glycation by ascorbic acid oxidation products leads to the aggregation of lens proteins.
Linetsky M, Shipova E, Cheng R, Ortwerth BJ. Linetsky M, et al. Among authors: ortwerth bj. Biochim Biophys Acta. 2008 Jan;1782(1):22-34. doi: 10.1016/j.bbadis.2007.10.003. Epub 2007 Oct 16. Biochim Biophys Acta. 2008. PMID: 18023423 Free PMC article.
LC-MS display of the total modified amino acids in cataract lens proteins and in lens proteins glycated by ascorbic acid in vitro.
Cheng R, Feng Q, Ortwerth BJ. Cheng R, et al. Among authors: ortwerth bj. Biochim Biophys Acta. 2006 May;1762(5):533-43. doi: 10.1016/j.bbadis.2006.01.009. Epub 2006 Feb 14. Biochim Biophys Acta. 2006. PMID: 16540295 Free article.
K2P--a novel cross-link from human lens protein.
Cheng R, Feng Q, Argirov OK, Ortwerth BJ. Cheng R, et al. Among authors: ortwerth bj. Ann N Y Acad Sci. 2005 Jun;1043:184-94. doi: 10.1196/annals.1333.023. Ann N Y Acad Sci. 2005. PMID: 16037238 Free PMC article.
Structure elucidation of a novel yellow chromophore from human lens protein.
Cheng R, Feng Q, Argirov OK, Ortwerth BJ. Cheng R, et al. Among authors: ortwerth bj. J Biol Chem. 2004 Oct 29;279(44):45441-9. doi: 10.1074/jbc.M405664200. Epub 2004 Aug 16. J Biol Chem. 2004. PMID: 15316021 Free article.
2-ammonio-6-(3-oxidopyridinium-1-yl)hexanoate (OP-lysine) is a newly identified advanced glycation end product in cataractous and aged human lenses.
Argirov OK, Lin B, Ortwerth BJ. Argirov OK, et al. Among authors: ortwerth bj. J Biol Chem. 2004 Feb 20;279(8):6487-95. doi: 10.1074/jbc.M309090200. Epub 2003 Nov 21. J Biol Chem. 2004. PMID: 14634019 Free article.
Activation of protein-bound copper ions during early glycation: study on two proteins.
Argirova MD, Ortwerth BJ. Argirova MD, et al. Among authors: ortwerth bj. Arch Biochem Biophys. 2003 Dec 1;420(1):176-84. doi: 10.1016/j.abb.2003.09.005. Arch Biochem Biophys. 2003. PMID: 14622988
Studies on the mechanism of the UVA light-dependent loss of glutathione reductase activity in human lenses.
Linetsky M, Hill JM, Chemoganskiy VG, Hu F, Ortwerth BJ. Linetsky M, et al. Among authors: ortwerth bj. Invest Ophthalmol Vis Sci. 2003 Sep;44(9):3920-6. doi: 10.1167/iovs.03-0390. Invest Ophthalmol Vis Sci. 2003. PMID: 12939310
Separation of the yellow chromophores in individual brunescent cataracts.
Cheng R, Lin B, Ortwerth BJ. Cheng R, et al. Among authors: ortwerth bj. Exp Eye Res. 2003 Sep;77(3):313-25. doi: 10.1016/s0014-4835(03)00131-3. Exp Eye Res. 2003. PMID: 12907164
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