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Persistent atrial fibrillation worsens heart rate variability, activity and heart rate, as shown by a continuous monitoring by implantable biventricular pacemakers in heart failure patients.
Puglisi A, Gasparini M, Lunati M, Sassara M, Padeletti L, Landolina M, Botto GL, Vincenti A, Bianchi S, Denaro A, Grammatico A, Boriani G; InSync III Italian Registry Investigators. Puglisi A, et al. J Cardiovasc Electrophysiol. 2008 Jul;19(7):693-701. doi: 10.1111/j.1540-8167.2007.01093.x. Epub 2008 Mar 4. J Cardiovasc Electrophysiol. 2008. PMID: 18328039 Clinical Trial.