Osborne MA - Search Results

1

Postsymptomatic restoration of SMN rescues the disease phenotype in a mouse model of severe spinal muscular atrophy.

Lutz CM, Kariya S, Patruni S, Osborne MA, Liu D, Henderson CE, Li DK, Pellizzoni L, Rojas J, Valenzuela DM, Murphy AJ, Winberg ML, Monani UR. Lutz CM, et al. Among authors: osborne ma. J Clin Invest. 2011 Aug;121(8):3029-41. doi: 10.1172/JCI57291. Epub 2011 Jul 25. J Clin Invest. 2011. PMID: 21785219 Free PMC article.

2

Systemic, postsymptomatic antisense oligonucleotide rescues motor unit maturation delay in a new mouse model for type II/III spinal muscular atrophy.

Bogdanik LP, Osborne MA, Davis C, Martin WP, Austin A, Rigo F, Bennett CF, Lutz CM. Bogdanik LP, et al. Among authors: osborne ma. Proc Natl Acad Sci U S A. 2015 Oct 27;112(43):E5863-72. doi: 10.1073/pnas.1509758112. Epub 2015 Oct 12. Proc Natl Acad Sci U S A. 2015. PMID: 26460027 Free PMC article.

3

Optimizing mouse models of neurodegenerative disorders: are therapeutics in sight?

Lutz CM, Osborne MA. Lutz CM, et al. Among authors: osborne ma. Future Neurol. 2013;9(1):67-75. doi: 10.2217/fnl.13.66. Epub 2013 Dec 16. Future Neurol. 2013. PMID: 29479291 Free PMC article.

4

Characterization of behavioral and neuromuscular junction phenotypes in a novel allelic series of SMA mouse models.

Osborne M, Gomez D, Feng Z, McEwen C, Beltran J, Cirillo K, El-Khodor B, Lin MY, Li Y, Knowlton WM, McKemy DD, Bogdanik L, Butts-Dehm K, Martens K, Davis C, Doty R, Wardwell K, Ghavami A, Kobayashi D, Ko CP, Ramboz S, Lutz C. Osborne M, et al. Hum Mol Genet. 2012 Oct 15;21(20):4431-47. doi: 10.1093/hmg/dds285. Epub 2012 Jul 16. Hum Mol Genet. 2012. PMID: 22802075 Free PMC article.

5

Survival motor neuron protein in motor neurons determines synaptic integrity in spinal muscular atrophy.

Martinez TL, Kong L, Wang X, Osborne MA, Crowder ME, Van Meerbeke JP, Xu X, Davis C, Wooley J, Goldhamer DJ, Lutz CM, Rich MM, Sumner CJ. Martinez TL, et al. Among authors: osborne ma. J Neurosci. 2012 Jun 20;32(25):8703-15. doi: 10.1523/JNEUROSCI.0204-12.2012. J Neurosci. 2012. PMID: 22723710 Free PMC article.

6

C57BL/6J congenic Prp-TDP43A315T mice develop progressive neurodegeneration in the myenteric plexus of the colon without exhibiting key features of ALS.

Hatzipetros T, Bogdanik LP, Tassinari VR, Kidd JD, Moreno AJ, Davis C, Osborne M, Austin A, Vieira FG, Lutz C, Perrin S. Hatzipetros T, et al. Brain Res. 2014 Oct 10;1584:59-72. doi: 10.1016/j.brainres.2013.10.013. Epub 2013 Oct 18. Brain Res. 2014. PMID: 24141148

7

Frataxin-deficient neurons and mice models of Friedreich ataxia are improved by TAT-MTScs-FXN treatment.

Britti E, Delaspre F, Feldman A, Osborne M, Greif H, Tamarit J, Ros J. Britti E, et al. J Cell Mol Med. 2018 Feb;22(2):834-848. doi: 10.1111/jcmm.13365. Epub 2017 Oct 5. J Cell Mol Med. 2018. PMID: 28980774 Free PMC article.

8

Through regulation of TCR expression levels, an Idd7 region gene(s) interactively contributes to the impaired thymic deletion of autoreactive diabetogenic CD8+ T cells in nonobese diabetic mice.

Serreze DV, Choisy-Rossi CM, Grier AE, Holl TM, Chapman HD, Gahagan JR, Osborne MA, Zhang W, King BL, Brown A, Roopenian D, Marron MP. Serreze DV, et al. Among authors: osborne ma. J Immunol. 2008 Mar 1;180(5):3250-9. doi: 10.4049/jimmunol.180.5.3250. J Immunol. 2008. PMID: 18292549

9

Idd9/11 genetic locus regulates diabetogenic activity of CD4 T-cells in nonobese diabetic (NOD) mice.

Chen YG, Scheuplein F, Osborne MA, Tsaih SW, Chapman HD, Serreze DV. Chen YG, et al. Among authors: osborne ma. Diabetes. 2008 Dec;57(12):3273-80. doi: 10.2337/db08-0767. Epub 2008 Sep 5. Diabetes. 2008. PMID: 18776136 Free PMC article.

10

Cellular expression requirements for inhibition of type 1 diabetes by a dominantly protective major histocompatibility complex haplotype.

Chen YG, Silveira PA, Osborne MA, Chapman HD, Serreze DV. Chen YG, et al. Among authors: osborne ma. Diabetes. 2007 Feb;56(2):424-30. doi: 10.2337/db06-1303. Diabetes. 2007. PMID: 17259387

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