Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Edit custom filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1968 1
1969 1
1971 1
1973 1
1976 4
1977 2
1978 1
1979 2
1980 3
1981 4
1982 5
1983 5
1984 4
1985 11
1986 10
1987 13
1988 8
1989 8
1990 17
1991 7
1992 13
1993 7
1994 9
1995 10
1996 11
1997 14
1998 12
1999 13
2000 11
2001 9
2002 14
2003 22
2004 12
2005 17
2006 18
2007 17
2008 11
2009 11
2010 16
2011 16
2012 20
2013 24
2014 28
2015 12
2016 8
2017 21
2018 27
2019 24
2020 31
2021 30
2022 25
2023 19
2024 35
2025 55
2026 25

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

681 results

Results by year

Filters applied: . Clear all
Page 1
Osmolar gap in hyponatraemia: An exploratory study.
Memon S, Saeed F, Alam A, Chughtai J, Imtiaz S. Memon S, et al. J Pak Med Assoc. 2024 Jun;74(6):1163-1166. doi: 10.47391/JPMA.10483. J Pak Med Assoc. 2024. PMID: 38948991 Free article.
The study involved categorising severity of hyponatraemia and volume status. The osmolar gap (OG) was calculated and categorised as either increased (OG>10) or normal (OG<10). ...These findings underscore the importance for clinicians to consider the osmola …
The study involved categorising severity of hyponatraemia and volume status. The osmolar gap (OG) was calculated and categoris …
Osmolar-gap in the setting of metformin-associated lactic acidosis: Case report and a literature review highlighting an apparently unusual association.
Elshafei MN, Alamin M, Mohamed MFH. Elshafei MN, et al. Medicine (Baltimore). 2020 Oct 9;99(41):e22492. doi: 10.1097/MD.0000000000022492. Medicine (Baltimore). 2020. PMID: 33031284 Free PMC article. Review.
RATIONALE: Metformin-associated lactic acidosis (MALA) is a rare adverse effect that has significant morbidity and mortality. MALA is a high anion gap (AG), nonosmolar acidosis. Associated osmolar-gap (OG) is rarely reported, so finding an OG may make the dia …
RATIONALE: Metformin-associated lactic acidosis (MALA) is a rare adverse effect that has significant morbidity and mortality. MALA is a high …
Approach to Patients With High Anion Gap Metabolic Acidosis: Core Curriculum 2021.
Fenves AZ, Emmett M. Fenves AZ, et al. Am J Kidney Dis. 2021 Oct;78(4):590-600. doi: 10.1053/j.ajkd.2021.02.341. Epub 2021 Aug 13. Am J Kidney Dis. 2021. PMID: 34400023 Review.
The anion gap (AG) is a mathematical construct that compares the blood sodium concentration with the sum of the chloride and bicarbonate concentrations. ...We also show how to calculate and, if necessary, correct the AG for hypoalbuminemia and severe hyperglycemia. …
The anion gap (AG) is a mathematical construct that compares the blood sodium concentration with the sum of the chloride and b …
Basic concepts and practical equations on osmolality: Biochemical approach.
Rasouli M. Rasouli M. Clin Biochem. 2016 Aug;49(12):936-41. doi: 10.1016/j.clinbiochem.2016.06.001. Epub 2016 Jun 22. Clin Biochem. 2016. PMID: 27343561 Review.
If the solute concentration (C) is expressed as mg/L, mg/dL and g%, osmolarity is calculated as: C.n' /MW, C.n' (10)/MW and C.n' (10(4))/MW respectively. Osmolality is milliosmoles of solutes per one kilogram (or liter) of water of solution (plasma) and is calculate …
If the solute concentration (C) is expressed as mg/L, mg/dL and g%, osmolarity is calculated as: C.n' /MW, C.n' (10)/MW and C. …
Drug-induced acid-base disorders.
Kitterer D, Schwab M, Alscher MD, Braun N, Latus J. Kitterer D, et al. Pediatr Nephrol. 2015 Sep;30(9):1407-23. doi: 10.1007/s00467-014-2958-5. Epub 2014 Nov 5. Pediatr Nephrol. 2015. PMID: 25370778 Review.
Highly sensitive diagnostic tools to distinguish the various ABDs include the anion gap and the serum osmolar gap. Drug-induced ABDs can be classified into five different categories in terms of their pathophysiology: (1) metabolic acidosis caused by acid over …
Highly sensitive diagnostic tools to distinguish the various ABDs include the anion gap and the serum osmolar gap. Drug …
Bridging the Gap.
Lee JT, Lechner MG, Vaidya A, Weinmann M. Lee JT, et al. N Engl J Med. 2019 Jan 31;380(5):e6. doi: 10.1056/NEJMimc1716605. N Engl J Med. 2019. PMID: 30699317 No abstract available.
Osmolar gap hyponatremia in critically ill patients: evidence for the sick cell syndrome?
Guglielminotti J, Pernet P, Maury E, Alzieu M, Vaubourdolle M, Guidet B, Offenstadt G. Guglielminotti J, et al. Crit Care Med. 2002 May;30(5):1051-5. doi: 10.1097/00003246-200205000-00016. Crit Care Med. 2002. PMID: 12006802
No difference of amino acids concentration was observed between osmolar gap and non-osmolar gap patients, and no correlation was observed between osmolar gap and amino acid concentration. Accumulation of ketone bodies and la …
No difference of amino acids concentration was observed between osmolar gap and non-osmolar gap patients, …
Factors influencing the serum osmolar gap.
Poulose V. Poulose V. Chest. 2002 Jul;122(1):381; author reply 381. doi: 10.1378/chest.122.1.381. Chest. 2002. PMID: 12114388 No abstract available.
Osmotic pressure-induced calcium response states.
Gao Z, Naruse K, Morimatsu M. Gao Z, et al. FEBS Open Bio. 2025 Oct;15(10):1714-1722. doi: 10.1002/2211-5463.70094. Epub 2025 Aug 29. FEBS Open Bio. 2025. PMID: 40883966 Free PMC article.
Mechanistically, these calcium signals originated from the endoplasmic reticulum via ryanodine receptor 2 and propagated to neighboring cells through Connexin 43-mediated gap junctions. These findings reveal a previously unrecognized role for calcium signaling in the acute …
Mechanistically, these calcium signals originated from the endoplasmic reticulum via ryanodine receptor 2 and propagated to neighboring cell …
The 'gap' in the 'plasma osmolar gap'.
Arora A. Arora A. BMJ Case Rep. 2013 Aug 8;2013:bcr2013200250. doi: 10.1136/bcr-2013-200250. BMJ Case Rep. 2013. PMID: 23929610 Free PMC article.
The diagnosis of ethylene glycol poisoning is not always straightforward and the commonly quoted 'plasma osmolar gap' is not sufficiently sensitive to exclude a small ingestion and has been reported to be normal in a number of serious exposures. The 'plasma osmol …
The diagnosis of ethylene glycol poisoning is not always straightforward and the commonly quoted 'plasma osmolar gap' is not s …
681 results