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Lasmiditan mechanism of action - review of a selective 5-HT1F agonist.
Clemow DB, Johnson KW, Hochstetler HM, Ossipov MH, Hake AM, Blumenfeld AM. Clemow DB, et al. Among authors: ossipov mh. J Headache Pain. 2020 Jun 10;21(1):71. doi: 10.1186/s10194-020-01132-3. J Headache Pain. 2020. PMID: 32522164 Free PMC article. Review.
Issues Impacting Adverse Event Frequency and Severity: Differences Between Randomized Phase 2 and Phase 3 Clinical Trials for Lasmiditan.
Kudrow D, Krege JH, Hundemer HP, Berg PH, Khanna R, Ossipov MH, Pozo-Rosich P. Kudrow D, et al. Among authors: ossipov mh. Headache. 2020 Mar;60(3):576-588. doi: 10.1111/head.13731. Epub 2020 Jan 13. Headache. 2020. PMID: 31943195 Free PMC article.
CGRP and the Trigeminal System in Migraine.
Iyengar S, Johnson KW, Ossipov MH, Aurora SK. Iyengar S, et al. Among authors: ossipov mh. Headache. 2019 May;59(5):659-681. doi: 10.1111/head.13529. Epub 2019 Apr 14. Headache. 2019. PMID: 30982963 Free PMC article. Review.
Designing safer analgesics: a focus on μ-opioid receptor pathways.
Pergolizzi JV Jr, LeQuang JA, Taylor R Jr, Ossipov MH, Colucci D, Raffa RB. Pergolizzi JV Jr, et al. Among authors: ossipov mh. Expert Opin Drug Discov. 2018 Oct;13(10):965-972. doi: 10.1080/17460441.2018.1511539. Epub 2018 Sep 3. Expert Opin Drug Discov. 2018. PMID: 30175624 Review.
Discovery of "folded DNA" structures in human cells: Potential drug targets.
Raffa RB, Pergolizzi JV Jr, Taylor R Jr, Ossipov MH; NEMA Research Group. Raffa RB, et al. Among authors: ossipov mh. J Clin Pharm Ther. 2019 Feb;44(1):125-128. doi: 10.1111/jcpt.12758. Epub 2018 Aug 25. J Clin Pharm Ther. 2019. PMID: 30144395
Differential effects of left and right neuropathy on opioid gene expression in lumbar spinal cord.
Kononenko O, Mityakina I, Galatenko V, Watanabe H, Bazov I, Gerashchenko A, Sarkisyan D, Iatsyshyna A, Yakovleva T, Tonevitsky A, Marklund N, Ossipov MH, Bakalkin G. Kononenko O, et al. Among authors: ossipov mh. Brain Res. 2018 Sep 15;1695:78-83. doi: 10.1016/j.brainres.2018.05.043. Epub 2018 May 28. Brain Res. 2018. PMID: 29852138
Efficacy and safety of galcanezumab for the prevention of episodic migraine: Results of the EVOLVE-2 Phase 3 randomized controlled clinical trial.
Skljarevski V, Matharu M, Millen BA, Ossipov MH, Kim BK, Yang JY. Skljarevski V, et al. Among authors: ossipov mh. Cephalalgia. 2018 Jul;38(8):1442-1454. doi: 10.1177/0333102418779543. Epub 2018 May 31. Cephalalgia. 2018. PMID: 29848108 Clinical Trial.
Indirect-acting strategy of opioid action instead of direct receptor activation: dual-acting enkephalinase inhibitors (DENKIs).
Raffa RB, Pergolizzi JV Jr, Taylor R Jr, Ossipov MH; By the NEMA Research Group. Raffa RB, et al. Among authors: ossipov mh. J Clin Pharm Ther. 2018 Aug;43(4):443-449. doi: 10.1111/jcpt.12687. Epub 2018 May 2. J Clin Pharm Ther. 2018. PMID: 29722031 Review.
Nature's first "atypical opioids": Kratom and mitragynines.
Raffa RB, Pergolizzi JV, Taylor R, Ossipov MH; NEMA Research Group. Raffa RB, et al. Among authors: ossipov mh. J Clin Pharm Ther. 2018 Jun;43(3):437-441. doi: 10.1111/jcpt.12676. Epub 2018 Mar 8. J Clin Pharm Ther. 2018. PMID: 29520812
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