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Evolution of gait abnormalities in SOD1(G93A) transgenic mice.
Mancuso R, Oliván S, Osta R, Navarro X. Mancuso R, et al. Brain Res. 2011 Aug 11;1406:65-73. doi: 10.1016/j.brainres.2011.06.033. Epub 2011 Jul 5. Brain Res. 2011. PMID: 21733494
Optimal methods to characterize the G93A mouse model of ALS.
Miana-Mena FJ, Muñoz MJ, Yagüe G, Mendez M, Moreno M, Ciriza J, Zaragoza P, Osta R. Miana-Mena FJ, et al. Amyotroph Lateral Scler Other Motor Neuron Disord. 2005 Mar;6(1):55-62. doi: 10.1080/14660820510026162. Amyotroph Lateral Scler Other Motor Neuron Disord. 2005. PMID: 16036427
Reduction in the motoneuron inhibitory/excitatory synaptic ratio in an early-symptomatic mouse model of amyotrophic lateral sclerosis.
Sunico CR, Domínguez G, García-Verdugo JM, Osta R, Montero F, Moreno-López B. Sunico CR, et al. Brain Pathol. 2011 Jan;21(1):1-15. doi: 10.1111/j.1750-3639.2010.00417.x. Brain Pathol. 2011. PMID: 20653686
Electrophysiological analysis of a murine model of motoneuron disease.
Mancuso R, Santos-Nogueira E, Osta R, Navarro X. Mancuso R, et al. Clin Neurophysiol. 2011 Aug;122(8):1660-70. doi: 10.1016/j.clinph.2011.01.045. Epub 2011 Feb 25. Clin Neurophysiol. 2011. PMID: 21354365
Levels of membrane fluidity in the spinal cord and the brain in an animal model of amyotrophic lateral sclerosis.
Miana-Mena FJ, Piedrafita E, González-Mingot C, Larrodé P, Muñoz MJ, Martínez-Ballarín E, Reiter RJ, Osta R, García JJ. Miana-Mena FJ, et al. J Bioenerg Biomembr. 2011 Apr;43(2):181-6. doi: 10.1007/s10863-011-9348-5. Epub 2011 Mar 31. J Bioenerg Biomembr. 2011. PMID: 21451979
Non-viral gene delivery of the GDNF, either alone or fused to the C-fragment of tetanus toxin protein, prolongs survival in a mouse ALS model.
Moreno-Igoa M, Calvo AC, Ciriza J, Muñoz MJ, Zaragoza P, Osta R. Moreno-Igoa M, et al. Restor Neurol Neurosci. 2012;30(1):69-80. doi: 10.3233/RNN-2011-0621. Restor Neurol Neurosci. 2012. PMID: 22124037
Genetic biomarkers for ALS disease in transgenic SOD1(G93A) mice.
Calvo AC, Manzano R, Atencia-Cibreiro G, Oliván S, Muñoz MJ, Zaragoza P, Cordero-Vázquez P, Esteban-Pérez J, García-Redondo A, Osta R. Calvo AC, et al. PLoS One. 2012;7(3):e32632. doi: 10.1371/journal.pone.0032632. Epub 2012 Mar 7. PLoS One. 2012. PMID: 22412900 Free PMC article.
Effect of genetic background on onset and disease progression in the SOD1-G93A model of amyotrophic lateral sclerosis.
Mancuso R, Oliván S, Mancera P, Pastén-Zamorano A, Manzano R, Casas C, Osta R, Navarro X. Mancuso R, et al. Amyotroph Lateral Scler. 2012 May;13(3):302-10. doi: 10.3109/17482968.2012.662688. Epub 2012 Mar 16. Amyotroph Lateral Scler. 2012. PMID: 22424126
Altered in vitro proliferation of mouse SOD1-G93A skeletal muscle satellite cells.
Manzano R, Toivonen JM, Calvo AC, Oliván S, Zaragoza P, Rodellar C, Montarras D, Osta R. Manzano R, et al. Neurodegener Dis. 2013;11(3):153-64. doi: 10.1159/000338061. Epub 2012 Jul 10. Neurodegener Dis. 2013. PMID: 22797053
Sigma-1R agonist improves motor function and motoneuron survival in ALS mice.
Mancuso R, Oliván S, Rando A, Casas C, Osta R, Navarro X. Mancuso R, et al. Neurotherapeutics. 2012 Oct;9(4):814-26. doi: 10.1007/s13311-012-0140-y. Neurotherapeutics. 2012. PMID: 22935988 Free PMC article.
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