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Year Number of Results
2009 2
2010 1
2011 2
2013 6
2014 2
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2016 9
2017 5
2018 4
2019 8
2020 11
2021 12
2022 3
2023 9
2024 13
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81 results

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Page 1
Cancer Cachexia: Its Mechanism and Clinical Significance.
Nishikawa H, Goto M, Fukunishi S, Asai A, Nishiguchi S, Higuchi K. Nishikawa H, et al. Int J Mol Sci. 2021 Aug 6;22(16):8491. doi: 10.3390/ijms22168491. Int J Mol Sci. 2021. PMID: 34445197 Free PMC article. Review.
Sex-specific cytotoxicity of ostarine in cardiomyocytes.
Leciejewska N, Pruszyńska-Oszmałek E, Nogowski L, Sassek M, Strowski MZ, Kołodziejski PA. Leciejewska N, et al. Mol Cell Endocrinol. 2023 Nov 1;577:112037. doi: 10.1016/j.mce.2023.112037. Epub 2023 Aug 3. Mol Cell Endocrinol. 2023. PMID: 37543162 Free article.
Ostarine is the most popular compound in the selective androgen receptor modulator group (SARMs). ...Taken together, our results suggest that ostarine is cardiotoxic which may be more relevant in males than in females....
Ostarine is the most popular compound in the selective androgen receptor modulator group (SARMs). ...Taken together, our results sugg …
Ostarine blunts the effect of endurance training on submaximal endurance in rats.
Vasilev V, Boyadjiev N, Hrischev P, Gerginska F, Delchev S, Arabadzhiyska D, Komrakova M, Boeker KO, Schilling AF, Georgieva K. Vasilev V, et al. Naunyn Schmiedebergs Arch Pharmacol. 2024 Sep;397(9):6523-6532. doi: 10.1007/s00210-024-03030-w. Epub 2024 Mar 7. Naunyn Schmiedebergs Arch Pharmacol. 2024. PMID: 38451281 Free PMC article.
The purpose of this study is to study the effects of ostarine alone and in combination with endurance training in sexually mature, male Wistar rats. ...Neither ostarine nor the training had a significant effect on the testis, liver, and heart weights. ...
The purpose of this study is to study the effects of ostarine alone and in combination with endurance training in sexually mature, ma …
Ostarine attenuates pyocyanin in Pseudomonas aeruginosa by interfering with quorum sensing systems.
Dong L, Sun L, Hu X, Nie T, Pang J, Wang X, Yang X, Li C, Yao K, Zhang Y, You X. Dong L, et al. J Antibiot (Tokyo). 2021 Dec;74(12):863-873. doi: 10.1038/s41429-021-00469-4. Epub 2021 Sep 3. J Antibiot (Tokyo). 2021. PMID: 34480092
Ostarine treatment significantly decreased the synthesis of pyocyanin without any bactericidal action. Besides, ostarine treatment did not affect the relative growth rate and cell morphology of bacteria. ...
Ostarine treatment significantly decreased the synthesis of pyocyanin without any bactericidal action. Besides, ostarine treat …
Nonsteroidal selective androgen receptor modulator Ostarine in cancer cachexia.
Zilbermint MF, Dobs AS. Zilbermint MF, et al. Future Oncol. 2009 Oct;5(8):1211-20. doi: 10.2217/fon.09.106. Future Oncol. 2009. PMID: 19852734 Review.
The newly developed nonsteroidal selective androgen receptor modulator Ostarine has demonstrated promising results in Phase I and II clinical trials, increasing total lean body mass, enhancing functional performance and decreasing total tissue percent fat. ...
The newly developed nonsteroidal selective androgen receptor modulator Ostarine has demonstrated promising results in Phase I and II …
Ostarine-Induced Myogenic Differentiation in C2C12, L6, and Rat Muscles.
Leciejewska N, Kołodziejski PA, Sassek M, Nogowski L, Małek E, Pruszyńska-Oszmałek E. Leciejewska N, et al. Int J Mol Sci. 2022 Apr 15;23(8):4404. doi: 10.3390/ijms23084404. Int J Mol Sci. 2022. PMID: 35457222 Free PMC article.
Ostarine (also known as enobosarm or Gtx-024) belongs to the selective androgen receptor modulators (SARMs). ...We aimed to investigate the effect of ostarine on the differentiation and metabolism of muscle. Using C2C12 and L6 cells, as well as muscles obtained from …
Ostarine (also known as enobosarm or Gtx-024) belongs to the selective androgen receptor modulators (SARMs). ...We aimed to investiga …
The Selective Androgen Receptor Modulator Ostarine Improves Bone Healing in Ovariectomized Rats.
Komrakova M, Furtwängler J, Hoffmann DB, Lehmann W, Schilling AF, Sehmisch S. Komrakova M, et al. Calcif Tissue Int. 2020 Feb;106(2):147-157. doi: 10.1007/s00223-019-00613-1. Epub 2019 Sep 17. Calcif Tissue Int. 2020. PMID: 31531719
Non-steroidal selective androgen receptor modulators, including ostarine, have been developed as an alternative to steroidal hormones. Ostarine has shown a beneficial effect on bone in experimental studies, but no data regarding the effect of ostarine on bone …
Non-steroidal selective androgen receptor modulators, including ostarine, have been developed as an alternative to steroidal hormones …
Clinical results in cachexia therapeutics.
Crawford J. Crawford J. Curr Opin Clin Nutr Metab Care. 2016 May;19(3):199-204. doi: 10.1097/MCO.0000000000000274. Curr Opin Clin Nutr Metab Care. 2016. PMID: 26974316 Review.
Ostarine does not enhance the metabolic effect of exercise in obese rats.
Leciejewska N, Pruszynska-Oszmalek E, Sassek M, Głowacki M, Lehmenn T, Rekas-Dudziak A, Nogowski L, Nowak KW, Kolodziejski PA. Leciejewska N, et al. J Physiol Pharmacol. 2023 Aug;74(4). doi: 10.26402/jpp.2023.4.06. Epub 2023 Oct 16. J Physiol Pharmacol. 2023. PMID: 37865959 Free article.
Our results indicated that ostarine had a lowering effect on cholesterol concentration in the serum (P<0.05). Moreover, when combining ostarine and exercise, additive changes were only observed in the levels of total and HDL cholesterol. No significant change was …
Our results indicated that ostarine had a lowering effect on cholesterol concentration in the serum (P<0.05). Moreover, when combi …
Activity and safety of enobosarm, a novel, oral, selective androgen receptor modulator, in androgen receptor-positive, oestrogen receptor-positive, and HER2-negative advanced breast cancer (Study G200802): a randomised, open-label, multicentre, multinational, parallel design, phase 2 trial.
Palmieri C, Linden H, Birrell SN, Wheelwright S, Lim E, Schwartzberg LS, Dwyer AR, Hickey TE, Rugo HS, Cobb P, O'Shaughnessy JA, Johnston S, Brufsky A, Tilley WD, Overmoyer B. Palmieri C, et al. Lancet Oncol. 2024 Mar;25(3):317-325. doi: 10.1016/S1470-2045(24)00004-4. Epub 2024 Feb 8. Lancet Oncol. 2024. PMID: 38342115 Free article. Clinical Trial.
81 results