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Page 1
Protection against high intravascular pressure in giraffe legs.
Petersen KK, Hørlyck A, Ostergaard KH, Andresen J, Broegger T, Skovgaard N, Telinius N, Laher I, Bertelsen MF, Grøndahl C, Smerup M, Secher NH, Brøndum E, Hasenkam JM, Wang T, Baandrup U, Aalkjaer C. Petersen KK, et al. Among authors: ostergaard kh. Am J Physiol Regul Integr Comp Physiol. 2013 Nov 1;305(9):R1021-30. doi: 10.1152/ajpregu.00025.2013. Epub 2013 Sep 4. Am J Physiol Regul Integr Comp Physiol. 2013. PMID: 24005251 Free article.
Pressure profile and morphology of the arteries along the giraffe limb.
Østergaard KH, Bertelsen MF, Brøndum ET, Aalkjaer C, Hasenkam JM, Smerup M, Wang T, Nyengaard JR, Baandrup U. Østergaard KH, et al. J Comp Physiol B. 2011 Jul;181(5):691-8. doi: 10.1007/s00360-010-0545-z. Epub 2011 Jan 5. J Comp Physiol B. 2011. PMID: 21207038
Jugular venous pooling during lowering of the head affects blood pressure of the anesthetized giraffe.
Brøndum E, Hasenkam JM, Secher NH, Bertelsen MF, Grøndahl C, Petersen KK, Buhl R, Aalkjaer C, Baandrup U, Nygaard H, Smerup M, Stegmann F, Sloth E, Ostergaard KH, Nissen P, Runge M, Pitsillides K, Wang T. Brøndum E, et al. Among authors: ostergaard kh. Am J Physiol Regul Integr Comp Physiol. 2009 Oct;297(4):R1058-65. doi: 10.1152/ajpregu.90804.2008. Epub 2009 Aug 5. Am J Physiol Regul Integr Comp Physiol. 2009. PMID: 19657096 Free article.
The giraffe kidney tolerates high arterial blood pressure by high renal interstitial pressure and low glomerular filtration rate.
Damkjaer M, Wang T, Brøndum E, Østergaard KH, Baandrup U, Hørlyck A, Hasenkam JM, Smerup M, Funder J, Marcussen N, Danielsen CC, Bertelsen MF, Grøndahl C, Pedersen M, Agger P, Candy G, Aalkjaer C, Bie P. Damkjaer M, et al. Among authors: ostergaard kh. Acta Physiol (Oxf). 2015 Aug;214(4):497-510. doi: 10.1111/apha.12531. Epub 2015 Jun 15. Acta Physiol (Oxf). 2015. PMID: 26010805
The thick left ventricular wall of the giraffe heart normalises wall tension, but limits stroke volume and cardiac output.
Smerup M, Damkjær M, Brøndum E, Baandrup UT, Kristiansen SB, Nygaard H, Funder J, Aalkjær C, Sauer C, Buchanan R, Bertelsen MF, Østergaard K, Grøndahl C, Candy G, Hasenkam JM, Secher NH, Bie P, Wang T. Smerup M, et al. J Exp Biol. 2016 Feb;219(Pt 3):457-63. doi: 10.1242/jeb.132753. Epub 2015 Dec 7. J Exp Biol. 2016. PMID: 26643090