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HLA-A*32:01 is strongly associated with vancomycin-induced drug reaction with eosinophilia and systemic symptoms.
Konvinse KC, Trubiano JA, Pavlos R, James I, Shaffer CM, Bejan CA, Schutte RJ, Ostrov DA, Pilkinton MA, Rosenbach M, Zwerner JP, Williams KB, Bourke J, Martinez P, Rwandamuriye F, Chopra A, Watson M, Redwood AJ, White KD, Mallal SA, Phillips EJ. Konvinse KC, et al. Among authors: ostrov da. J Allergy Clin Immunol. 2019 Jul;144(1):183-192. doi: 10.1016/j.jaci.2019.01.045. Epub 2019 Feb 16. J Allergy Clin Immunol. 2019. PMID: 30776417 Free PMC article.
Drug hypersensitivity caused by alteration of the MHC-presented self-peptide repertoire.
Ostrov DA, Grant BJ, Pompeu YA, Sidney J, Harndahl M, Southwood S, Oseroff C, Lu S, Jakoncic J, de Oliveira CA, Yang L, Mei H, Shi L, Shabanowitz J, English AM, Wriston A, Lucas A, Phillips E, Mallal S, Grey HM, Sette A, Hunt DF, Buus S, Peters B. Ostrov DA, et al. Proc Natl Acad Sci U S A. 2012 Jun 19;109(25):9959-64. doi: 10.1073/pnas.1207934109. Epub 2012 May 29. Proc Natl Acad Sci U S A. 2012. PMID: 22645359 Free PMC article.
T cell-mediated hypersensitivity reactions to drugs.
Pavlos R, Mallal S, Ostrov D, Buus S, Metushi I, Peters B, Phillips E. Pavlos R, et al. Annu Rev Med. 2015;66:439-54. doi: 10.1146/annurev-med-050913-022745. Epub 2014 Oct 27. Annu Rev Med. 2015. PMID: 25386935 Free PMC article. Review.
Abacavir-reactive memory T cells are present in drug naïve individuals.
Lucas A, Lucas M, Strhyn A, Keane NM, McKinnon E, Pavlos R, Moran EM, Meyer-Pannwitt V, Gaudieri S, D'Orsogna L, Kalams S, Ostrov DA, Buus S, Peters B, Mallal S, Phillips E. Lucas A, et al. Among authors: ostrov da. PLoS One. 2015 Feb 12;10(2):e0117160. doi: 10.1371/journal.pone.0117160. eCollection 2015. PLoS One. 2015. PMID: 25674793 Free PMC article.
Acyclovir Has Low but Detectable Influence on HLA-B*57:01 Specificity without Inducing Hypersensitivity.
Metushi IG, Wriston A, Banerjee P, Gohlke BO, English AM, Lucas A, Moore C, Sidney J, Buus S, Ostrov DA, Mallal S, Phillips E, Shabanowitz J, Hunt DF, Preissner R, Peters B. Metushi IG, et al. Among authors: ostrov da. PLoS One. 2015 May 29;10(5):e0124878. doi: 10.1371/journal.pone.0124878. eCollection 2015. PLoS One. 2015. PMID: 26024233 Free PMC article.
Report from the National Institute of Allergy and Infectious Diseases workshop on drug allergy.
Wheatley LM, Plaut M, Schwaninger JM, Banerji A, Castells M, Finkelman FD, Gleich GJ, Guttman-Yassky E, Mallal SA, Naisbitt DJ, Ostrov DA, Phillips EJ, Pichler WJ, Platts-Mills TA, Roujeau JC, Schwartz LB, Trepanier LA. Wheatley LM, et al. Among authors: ostrov da. J Allergy Clin Immunol. 2015 Aug;136(2):262-71.e2. doi: 10.1016/j.jaci.2015.05.027. J Allergy Clin Immunol. 2015. PMID: 26254053 Free PMC article.
144 results