Othman AA - Search Results

1

Population pharmacokinetics of levodopa in subjects with advanced Parkinson's disease: levodopa-carbidopa intestinal gel infusion vs. oral tablets.

Othman AA, Dutta S. Othman AA, et al. Br J Clin Pharmacol. 2014 Jul;78(1):94-105. doi: 10.1111/bcp.12324. Br J Clin Pharmacol. 2014. PMID: 24433449 Free PMC article. Clinical Trial.

2

Single- and multiple-dose pharmacokinetics, safety, and tolerability of the selective alpha7 neuronal nicotinic receptor agonist, ABT-107, in healthy human volunteers.

Othman AA, Lenz RA, Zhang J, Li J, Awni WM, Dutta S. Othman AA, et al. J Clin Pharmacol. 2011 Apr;51(4):512-26. doi: 10.1177/0091270010370460. Epub 2010 May 21. J Clin Pharmacol. 2011. PMID: 20495134 Clinical Trial.

3

Pharmacokinetics of the TRPV1 antagonist ABT-102 in healthy human volunteers: population analysis of data from 3 phase 1 trials.

Othman AA, Nothaft W, Awni WM, Dutta S. Othman AA, et al. J Clin Pharmacol. 2012 Jul;52(7):1028-41. doi: 10.1177/0091270011407497. Epub 2011 May 12. J Clin Pharmacol. 2012. PMID: 21566201

4

Effects of the TRPV1 antagonist ABT-102 on body temperature in healthy volunteers: pharmacokinetic/ pharmacodynamic analysis of three phase 1 trials.

Othman AA, Nothaft W, Awni WM, Dutta S. Othman AA, et al. Br J Clin Pharmacol. 2013 Apr;75(4):1029-40. doi: 10.1111/j.1365-2125.2012.04405.x. Br J Clin Pharmacol. 2013. PMID: 22966986 Free PMC article. Clinical Trial.

5

Safety, tolerability and pharmacokinetics of the histamine H3 receptor antagonist, ABT-288, in healthy young adults and elderly volunteers.

Othman AA, Haig G, Florian H, Locke C, Zhang J, Dutta S. Othman AA, et al. Br J Clin Pharmacol. 2013 May;75(5):1299-311. doi: 10.1111/j.1365-2125.2012.04472.x. Br J Clin Pharmacol. 2013. PMID: 23016924 Free PMC article. Clinical Trial.

6

Pharmacokinetics of levodopa, carbidopa, and 3-O-methyldopa following 16-hour jejunal infusion of levodopa-carbidopa intestinal gel in advanced Parkinson's disease patients.

Nyholm D, Odin P, Johansson A, Chatamra K, Locke C, Dutta S, Othman AA. Nyholm D, et al. Among authors: othman aa. AAPS J. 2013 Apr;15(2):316-23. doi: 10.1208/s12248-012-9439-1. Epub 2012 Dec 11. AAPS J. 2013. PMID: 23229334 Free PMC article.

7

The H3 antagonist ABT-288 is tolerated at significantly higher exposures in subjects with schizophrenia than in healthy volunteers.

Othman AA, Haig G, Florian H, Locke C, Gertsik L, Dutta S. Othman AA, et al. Br J Clin Pharmacol. 2014 Jun;77(6):965-74. doi: 10.1111/bcp.12281. Br J Clin Pharmacol. 2014. PMID: 24215171 Free PMC article. Clinical Trial.

8

Continuous intrajejunal infusion of levodopa-carbidopa intestinal gel for patients with advanced Parkinson's disease: a randomised, controlled, double-blind, double-dummy study.

Olanow CW, Kieburtz K, Odin P, Espay AJ, Standaert DG, Fernandez HH, Vanagunas A, Othman AA, Widnell KL, Robieson WZ, Pritchett Y, Chatamra K, Benesh J, Lenz RA, Antonini A; LCIG Horizon Study Group. Olanow CW, et al. Among authors: othman aa. Lancet Neurol. 2014 Feb;13(2):141-9. doi: 10.1016/S1474-4422(13)70293-X. Epub 2013 Dec 20. Lancet Neurol. 2014. PMID: 24361112 Free PMC article. Clinical Trial.

9

Population pharmacokinetics of daclizumab high-yield process in healthy volunteers: integrated analysis of intravenous and subcutaneous, single- and multiple-dose administration.

Othman AA, Tran JQ, Tang MT, Dutta S. Othman AA, et al. Clin Pharmacokinet. 2014 Oct;53(10):907-18. doi: 10.1007/s40262-014-0159-9. Clin Pharmacokinet. 2014. PMID: 25212703 Clinical Trial.

10

Jejunal Infusion of levodopa-carbidopa intestinal gel versus oral administration of levodopa-carbidopa tablets in japanese subjects with advanced Parkinson's disease: pharmacokinetics and pilot efficacy and safety.

Othman AA, Chatamra K, Mohamed ME, Dutta S, Benesh J, Yanagawa M, Nagai M. Othman AA, et al. Clin Pharmacokinet. 2015 Sep;54(9):975-84. doi: 10.1007/s40262-015-0265-3. Clin Pharmacokinet. 2015. PMID: 25875940 Free PMC article. Clinical Trial.

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