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Evans Blue is an inhibitor of nuclear factor-kappa B (NF-kappaB)-DNA binding.
Sharma RK, Otsuka M, Pande V, Inoue J, João Ramos M. Sharma RK, et al. Bioorg Med Chem Lett. 2004 Dec 20;14(24):6123-7. doi: 10.1016/j.bmcl.2004.07.096. Bioorg Med Chem Lett. 2004. PMID: 15546742
Aurine tricarboxylic acid, a potent metal-chelating inhibitor of NFkappaB-DNA binding.
Sharma RK, Garg BS, Kurosaki H, Goto M, Otsuka M, Yamamoto T, Inoue J. Sharma RK, et al. Bioorg Med Chem. 2000 Jul;8(7):1819-23. doi: 10.1016/s0968-0896(00)00109-7. Bioorg Med Chem. 2000. PMID: 10976530
A novel metal-chelating inhibitor of protein farnesyltransferase.
Hamasaki A, Naka H, Tamanoi F, Umezawa K, Otsuka M. Hamasaki A, et al. Bioorg Med Chem Lett. 2003 May 5;13(9):1523-6. doi: 10.1016/s0960-894x(03)00183-5. Bioorg Med Chem Lett. 2003. PMID: 12699746
Inhibitory activities against topoisomerase I and II by polyhydroxybenzoyl amide derivatives and their structure-activity relationship.
Abdel-Aziz M, Matsuda K, Otsuka M, Uyeda M, Okawara T, Suzuki K. Abdel-Aziz M, et al. Bioorg Med Chem Lett. 2004 Apr 5;14(7):1669-72. doi: 10.1016/j.bmcl.2004.01.060. Bioorg Med Chem Lett. 2004. PMID: 15026047
o-, m-, p-Phenylenediamines having 2,3,4-trihydroxy, 3,4 dihydroxy, and 4-hydroxybenzoyl moieties were prepared and their inhibitory activities were measured against topoisomerase I and II. ...
o-, m-, p-Phenylenediamines having 2,3,4-trihydroxy, 3,4 dihydroxy, and 4-hydroxybenzoyl moieties were prepared and their inhibitory …
A molecular modeling study of inhibitors of nuclear factor kappa-B (p50)--DNA binding.
Pande V, Sharma RK, Inoue J, Otsuka M, Ramos MJ. Pande V, et al. J Comput Aided Mol Des. 2003 Dec;17(12):825-36. doi: 10.1023/b:jcam.0000021835.72265.63. J Comput Aided Mol Des. 2003. PMID: 15124931
Inhibitory activities against topoisomerase I and II by isoaurostatin derivatives and their structure-activity relationships.
Suzuki K, Okawara T, Higashijima T, Yokomizo K, Mizushima T, Otsuka M. Suzuki K, et al. Bioorg Med Chem Lett. 2005 Apr 15;15(8):2065-8. doi: 10.1016/j.bmcl.2005.02.052. Bioorg Med Chem Lett. 2005. PMID: 15808469
Biological evaluation, chelation, and molecular modeling studies of novel metal-chelating inhibitors of NF-kappaB-DNA binding: structure activity relationships.
Sharma RK, Chopra S, Sharma SD, Pande V, Ramos MJ, Meguro K, Inoue J, Otsuka M. Sharma RK, et al. J Med Chem. 2006 Jun 15;49(12):3595-601. doi: 10.1021/jm050617x. J Med Chem. 2006. PMID: 16759101
Antiviral activities against herpes simplex virus type 1 by HPH derivatives and their structure-activity relationships.
Hosono T, Yokomizo K, Hamasaki A, Okamoto Y, Okawara T, Otsuka M, Mukai R, Suzuki K. Hosono T, et al. Bioorg Med Chem Lett. 2008 Jan 1;18(1):371-4. doi: 10.1016/j.bmcl.2007.10.065. Epub 2007 Oct 24. Bioorg Med Chem Lett. 2008. PMID: 17981031
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