Otvos L Jr - Search Results

1

Big peptide drugs in a small molecule world.

Otvos L Jr, Wade JD. Otvos L Jr, et al. Front Chem. 2023 Dec 7;11:1302169. doi: 10.3389/fchem.2023.1302169. eCollection 2023. Front Chem. 2023. PMID: 38144886 Free PMC article. Review.

2

Influence of Substitutions in the Binding Motif of Proline-Rich Antimicrobial Peptide ARV-1502 on 70S Ribosome Binding and Antimicrobial Activity.

Brakel A, Krizsan A, Itzenga R, Kraus CN, Otvos L Jr, Hoffmann R. Brakel A, et al. Among authors: otvos l jr. Int J Mol Sci. 2022 Mar 15;23(6):3150. doi: 10.3390/ijms23063150. Int J Mol Sci. 2022. PMID: 35328571 Free PMC article.

3

Functional Effects of ARV-1502 Analogs Against Bacterial Hsp70 and Implications for Antimicrobial Activity.

Brakel A, Kolano L, Kraus CN, Otvos L Jr, Hoffmann R. Brakel A, et al. Among authors: otvos l jr. Front Chem. 2022 Feb 9;10:798006. doi: 10.3389/fchem.2022.798006. eCollection 2022. Front Chem. 2022. PMID: 35223768 Free PMC article.

4

Leptin Receptor Blockade Attenuates Hypertension, but Does Not Affect Ventilatory Response to Hypoxia in a Model of Polygenic Obesity.

Kim LJ, Shin MK, Pho H, Otvos L Jr, Tufik S, Andersen ML, Pham LV, Polotsky VY. Kim LJ, et al. Among authors: otvos l jr. Front Physiol. 2021 Jul 2;12:688375. doi: 10.3389/fphys.2021.688375. eCollection 2021. Front Physiol. 2021. PMID: 34276408 Free PMC article.

5

Potential Adiponectin Receptor Response Modifier Therapeutics.

Otvos L Jr. Otvos L Jr. Front Endocrinol (Lausanne). 2019 Aug 13;10:539. doi: 10.3389/fendo.2019.00539. eCollection 2019. Front Endocrinol (Lausanne). 2019. PMID: 31456747 Free PMC article. Review.

6

Advantage of a Narrow Spectrum Host Defense (Antimicrobial) Peptide Over a Broad Spectrum Analog in Preclinical Drug Development.

Ostorhazi E, Hoffmann R, Herth N, Wade JD, Kraus CN, Otvos L Jr. Ostorhazi E, et al. Among authors: otvos l jr. Front Chem. 2018 Aug 21;6:359. doi: 10.3389/fchem.2018.00359. eCollection 2018. Front Chem. 2018. PMID: 30186829 Free PMC article.

7

Synergy Between Proline-Rich Antimicrobial Peptides and Small Molecule Antibiotics Against Selected Gram-Negative Pathogens in vitro and in vivo.

Otvos L Jr, Ostorhazi E, Szabo D, Zumbrun SD, Miller LL, Halasohoris SA, Desai PD, Int Veldt SM, Kraus CN. Otvos L Jr, et al. Front Chem. 2018 Aug 14;6:309. doi: 10.3389/fchem.2018.00309. eCollection 2018. Front Chem. 2018. PMID: 30155456 Free PMC article.

8

Transdermally administered proline-arginine-rich host defense peptides show systemic efficacy in a lethal mouse bacteremia model.

Ostorhazi E, Horvath A, Szabo D, Otvos L Jr. Ostorhazi E, et al. Among authors: otvos l jr. Amino Acids. 2017 Sep;49(9):1647-1651. doi: 10.1007/s00726-017-2457-7. Epub 2017 Jun 29. Amino Acids. 2017. PMID: 28664267

9

C-Terminal Modification and Multimerization Increase the Efficacy of a Proline-Rich Antimicrobial Peptide.

Li W, O'Brien-Simpson NM, Yao S, Tailhades J, Reynolds EC, Dawson RM, Otvos L Jr, Hossain MA, Separovic F, Wade JD. Li W, et al. Among authors: otvos l jr. Chemistry. 2017 Jan 5;23(2):390-396. doi: 10.1002/chem.201604172. Epub 2016 Nov 16. Chemistry. 2017. PMID: 27862429

10

Immunomodulatory effects of anti-microbial peptides.

Otvos L Jr. Otvos L Jr. Acta Microbiol Immunol Hung. 2016 Sep;63(3):257-277. doi: 10.1556/030.63.2016.005. Epub 2016 Aug 19. Acta Microbiol Immunol Hung. 2016. PMID: 27539330 Review.

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