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Mutations in cardiac T-box factor gene TBX20 are associated with diverse cardiac pathologies, including defects of septation and valvulogenesis and cardiomyopathy.
Kirk EP, Sunde M, Costa MW, Rankin SA, Wolstein O, Castro ML, Butler TL, Hyun C, Guo G, Otway R, Mackay JP, Waddell LB, Cole AD, Hayward C, Keogh A, Macdonald P, Griffiths L, Fatkin D, Sholler GF, Zorn AM, Feneley MP, Winlaw DS, Harvey RP. Kirk EP, et al. Among authors: otway r. Am J Hum Genet. 2007 Aug;81(2):280-91. doi: 10.1086/519530. Epub 2007 Jun 15. Am J Hum Genet. 2007. PMID: 17668378 Free PMC article.
Functional characterization of a novel mutation in NKX2-5 associated with congenital heart disease and adult-onset cardiomyopathy.
Costa MW, Guo G, Wolstein O, Vale M, Castro ML, Wang L, Otway R, Riek P, Cochrane N, Furtado M, Semsarian C, Weintraub RG, Yeoh T, Hayward C, Keogh A, Macdonald P, Feneley M, Graham RM, Seidman JG, Seidman CE, Rosenthal N, Fatkin D, Harvey RP. Costa MW, et al. Among authors: otway r. Circ Cardiovasc Genet. 2013 Jun;6(3):238-47. doi: 10.1161/CIRCGENETICS.113.000057. Epub 2013 May 9. Circ Cardiovasc Genet. 2013. PMID: 23661673 Free PMC article.
Atrial fibrillation--a new cardiac channelopathy.
Otway R, Vandenberg JI, Fatkin D. Otway R, et al. Heart Lung Circ. 2007 Oct;16(5):356-60. doi: 10.1016/j.hlc.2007.07.003. Epub 2007 Sep 4. Heart Lung Circ. 2007. PMID: 17768091 Review.
Genetics of dilated cardiomyopathy.
Fatkin D, Otway R, Richmond Z. Fatkin D, et al. Among authors: otway r. Heart Fail Clin. 2010 Apr;6(2):129-40. doi: 10.1016/j.hfc.2009.11.003. Heart Fail Clin. 2010. PMID: 20347783 Review.
Investigation of association between PFO complicated by cryptogenic stroke and a common variant of the cardiac transcription factor GATA4.
Moradi Marjaneh M, Kirk EP, Posch MG, Ozcelik C, Berger F, Hetzer R, Otway R, Butler TL, Blue GM, Griffiths LR, Fatkin D, Martinson JJ, Winlaw DS, Feneley MP, Harvey RP. Moradi Marjaneh M, et al. Among authors: otway r. PLoS One. 2011;6(6):e20711. doi: 10.1371/journal.pone.0020711. Epub 2011 Jun 6. PLoS One. 2011. PMID: 21673957 Free PMC article.
Genes and atrial fibrillation: a new look at an old problem.
Fatkin D, Otway R, Vandenberg JI. Fatkin D, et al. Among authors: otway r. Circulation. 2007 Aug 14;116(7):782-92. doi: 10.1161/CIRCULATIONAHA.106.688889. Circulation. 2007. PMID: 17698744 Review. No abstract available.
Epistatic effects of potassium channel variation on cardiac repolarization and atrial fibrillation risk.
Mann SA, Otway R, Guo G, Soka M, Karlsdotter L, Trivedi G, Ohanian M, Zodgekar P, Smith RA, Wouters MA, Subbiah R, Walker B, Kuchar D, Sanders P, Griffiths L, Vandenberg JI, Fatkin D. Mann SA, et al. Among authors: otway r. J Am Coll Cardiol. 2012 Mar 13;59(11):1017-25. doi: 10.1016/j.jacc.2011.11.039. J Am Coll Cardiol. 2012. PMID: 22402074 Free article.
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