Inhibition of phenylalanine hydroxylase, a pterin-requiring monooxygenase, by oudenone and its derivatives.
Koizumi S, Nagatsu T, Iinuma H, Ohno M, Takeuchi T, Umezawa H.
Koizumi S, et al.
J Antibiot (Tokyo). 1982 Apr;35(4):458-62. doi: 10.7164/antibiotics.35.458.
J Antibiot (Tokyo). 1982.
PMID: 7096201
Free article.
Phenylalanine hydroxylase was shown to be inhibited by oudenone and its derivatives in vitro. At a concentration of 2.3 x 10(-3) M, oudenone inhibited phenylalanine hydroxylase by 50%, and some of the oudenone derivatives showed more potent inhibition. ...A d …
Phenylalanine hydroxylase was shown to be inhibited by oudenone and its derivatives in vitro. At a concentration of 2.3 x 10(-3) M, …